Valencia

• Safety and Efficacy of VX-828/Deutivacaftor Combination Therapy With and Without Tezacaftor in Subjects With Cystic Fibrosis Pending
  2025-523400-72-00 4 Cystic fibrosis
• An efficacy and safety study of cenegermin ophthalmic solution compared with vehicle in the treatment of PCED Pending
  2025-523443-35-00 5 Persistent Corneal Epithelial Defect (PCED)
• A Study of S241656 in Patients With KRAS, BRAF and Other Selected RAS/MAPK Mutation-Positive Malignancies Pending
  2025-523474-16-00 7 Malignancies with Documented KRAS, BRAF and Other Selected RAS/MAPK Mu
• Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes Pending
  2025-523486-17-00 5 Obesity
• Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC) (RASolute 304) Pending
  2025-523495-23-00 5 Resected Pancreatic Ductal Adenocarcinoma (PDAC)
• Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight and Diabetes Pending
  2025-523510-87-00 5 Obesity
• A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorect … Pending
  2025-523521-18-00 5 Metastatic Colorectal Cancer
• A Study to Learn about the Study Medicine called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers Pending
  2025-523526-40-00 9 Advanced Solid Tumors
• A study to investigate dabogratinib (TYRA-300) in participants with Low Grade Upper Tract Urothelial Carcinoma Pending
  2025-523539-20-00 4 Low Grade Upper Tract Urothelial Carcinoma
• A phase 3 trial comparing elritercept versus epoetin alfa for treatment of anemia due to lower-risk MDS in ESA-naïve adults who require RBC … Pending
  2025-523544-12-00 5 Myelodysplastic neoplasms/syndromes (MDS)
• A Study of Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants with Unresectable Stage III NSCLC Pending
  2025-523576-23-00 5 Unresectable Stage III non-small cell lung cancer without progression
• Study to assess how safe and effective is HRX215 in participants who underwent minor and major liver surgery due to colon carcinoma metastas … Pending
  2025-523630-59-00 9 colon carcinoma metastases
• A Randomized, Double-Blind, Phase 3 Study of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treat … Pending
  2025-523735-19-00 5 Metastatic Microsatellite Stable Colorectal Cancer
• A study testing the medicine angiotensin II in patients of 0–17 years with a life-threateningly low blood pressure Pending
  2025-523750-14-00 5 refractory hypotension in distributive shock
• TGD001 Treatment in Thrombotic Microangiopathies Pending
  2025-523802-34-00 9 Immune-Mediated Thrombotic Thrombocytopenic Purpura
• A study in people with advanced extrapulmonary neuroendocrine cancer to compare obrixtamig plus carboplatin and etoposide treatment with sta … Pending
  2025-523869-22-00 5 advanced or metastatic extrapulmonary neuroendocrine carcinoma
• Study of IBI3009 alone or in combination with other therapies for extensive-stage small cell lung cancer Pending
  2025-523972-21-00 7 Extensive-Stage Small Cell Lung Cancer
• ​​AMG 436 as monotherapy and combination therapy in participants with Microsatellite Instability-High/Mismatch Repair Deficient Solid Tumors … Pending
  2025-524056-63-00 1 microsatellite instability high/mismatch repair deficient (MSI-H/dMMR)
• A clinical trial to provide continued access to remibrutinib (LOU064) for people who are benefiting from it in a previous remibrutinib trial Pending
  2025-524078-40-00 5 Chronic Spontaneous Urticaria
• A Phase II, Open-Label Randomized Study of Intravenous Tambiciclib in Combination with the Standard of care Venetoclax and Azacitidine in Pa … Pending
  2025-524308-31-00 4 Acute myeloid leukemia
• Phase III randomized international open label clinical trial of treatment Intensification with docetaxel plus apalutamide in patients with m … Pending
  2025-524408-30-01 5 Metastatic hormone-sensitive prostate cancer
• PHASE IB/II STUDY TO EVALUATE SAFETY AND PRELIMINARY EFFICACY OF ZANIDATAMAB IN COMBINATION WITH TUCATINIB AND CHEMOTHERAPY (CAPECITABINE OR … Pending
  2025-524613-89-00 9 HER2 positive advanced breast cancer
• Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia Pending
  2025-524810-28-00 5 Acute Promyelocytic Leukemia
• Phase I, first-in-human clinical trial to evaluate safety of infusion of STAb-T19 cells: genetically modified T lymphocytes secreting αCD19x … Pending
  2025-524814-27-00 1 Malignant B-cell neoplasms

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