Healthy women aged 18-70 either carriers of a germline pathogenetic variant (BRCA1, BRCA2, PALB2, ATM, CHEK2, CDH1, RAD51C or RAD51D) or with a breast cancer risk >5% at 10 years (according to the Tyrer-Cuzick model or the Breast Cancer Surveillance Consortium Risk models) or with a previously treated breast IEN (intraepithelial neoplasia).

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