Patients with a histological diagnosis of mismatch- repair deficient high risk endometrial cancer (MMRd HREC; no POLEmut; all histology including carcinosarcoma), Stage IB/II with LVSI or stage IIIA-C. Patients are treated with curative intent, after surgery (hysterectomy and bilateralsalpingo-oophorectomy, with or without lymphadenectomy or sentinel node biopsy), without signs of residual disease or distant metastases.

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