Decitabine — Drug Intelligence | 11 EU Trials

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11 Registered trials

4 Recruiting

7 Completed trials

11 Sponsors

12 Countries

Phase III

Phase II

Phase III: 2 Phase II: 7 Phase I (Other): 1 Phase I (FiH): 1

Oversight events:

1 serious breach across 1 trial

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Indications tested

Myelodysplastic syndrome 2 Acute myeloid leukaemia 1

Sponsors using this IMP

Akershus University Hospital 1 Fondazione Gimema Franco Mandelli Onlus 1 Fondazione NIBIT Onlus 1 Gruppo Italiano Per Il Trapianto Di Midollo Osseo Cellule Staminali Emopoietiche E Terapia Cellulare 1 Haemato Oncology Foundation For Adults Netherlands 1 Immatics Biotechnologies GmbH 1 Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori IRST S.r.l. 1 Nerviano Medical Sciences S.r.l. 1 Sellas Life Sciences Group Inc. 1 Taiho Oncology Inc. 1 Universitaetsklinikum Tuebingen 1

All trials

11 total

IMPACT-AML: A RANDOMIZED PRAGMATIC CLINICAL TRIAL FOR RELAPSE OR REFRACTORY ACUTE MYELOID LEUKEMIA Recruiting

2024-514517-35-00 Phase III 7 countries Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori IRST S.r.l.
A randomized, run-in, phase II study of nivolumab combined with ipilimumab and oral decitabine/cedazuridine (ASTX727) or nivolumab combined … Recruiting

2024-518891-29-00 Phase II 1 country Fondazione NIBIT Onlus
Phase II study of (early) combination salvage therapy with Venetoclax and intensified Decitabine in Relapsed/Refractory AML Recruiting

2022-502665-15-00 Phase II 1 country Universitaetsklinikum Tuebingen
A Phase I/II First-In-Human Clinical Trial to Evaluate the Safety, Tolerability and Anti-Tumor Activity of IMA402, a Bispecific T Cell-Engag… Recruiting

2022-503133-54-00 Phase I (FiH) 2 countries Immatics Biotechnologies GmbH
Study aimed at evaluating the efficacy of a combination treatment (decitabine and venetoclax) in patients with Acute Myeliode Leukemia who a… Ended

2023-510241-16-00 Phase II 1 country Fondazione Gimema Franco Mandelli Onlus
A Study of the Efficacy and Safety of Galinpepimut-S (GPS) for the Treatment of Acute Myeloid Leukemia Compared to Investigator's Choice of … Ended

2024-516405-23-00 Phase III 5 countries Sellas Life Sciences Group Inc.
A randomized phase II multicenter study to assess the tolerability and efficacy of the addition of midostaurin to 10-day decitabine in unfit… Ended

2023-503829-18-00 Phase II 2 countries Haemato Oncology Foundation For Adults Netherlands
A trial to learn how well NMS-01940153E works in combination with atezolizumab and priming administration of decitabine or with atezolizumab… Ended

2024-516737-12-00 Phase II 2 countries Nerviano Medical Sciences S.r.l.
A Randomized, Open-Label, Phase 1-2 Study of ASTX727 Low Dose (ASTX727 LD) Extended Schedule in Subjects with Lower Risk (IPSS Low or Interm… Ended

2024-516296-32-00 Phase I (Other) 3 countries Taiho Oncology Inc.
VEN-DEC GITMO Study Ended

2024-518792-54-00 Phase II 1 country Gruppo Italiano Per Il Trapianto Di Midollo Osseo Cellule Staminali Emopoietiche…
Precision therapy versus standard therapy in Acute Myeloid Leukaemia and Myelodysplastic syndrome in elderly (PALM) – a phase II randomized … Ended

2023-509092-16-00 Phase II 1 country Akershus University Hospital

Showing 1–11 of 11 trials

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