Iduronate-2-Sulfatase Fused To A Fc Polypeptide That Binds To The Human Transferrin Receptor

3 trials 2 recruiting

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3 Registered trials

2 Recruiting

1 Completed trials

1 Sponsors

8 Countries

Phase III

Phase II/III

Phase I (FiH)

Phase III: 1 Phase II/III: 1 Phase I (FiH): 1

Sponsors using this IMP

Denali Therapeutics Inc. 3

All trials

3 total

An Extension study of the Long-Term Safety, Tolerability, and Efficacy of DNL310 in Participants With Mucopolysaccharidosis Type II (MPS II)… Recruiting

2023-503837-23-00 Phase III 8 countries Denali Therapeutics Inc.
A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric and Young Adult Participants With Neu… Recruiting

2024-510990-21-00 Phase II/III 8 countries Denali Therapeutics Inc.
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL310 in Pediatric Participants with Hunter Syndrome Ended

2023-508619-22-00 Phase I (FiH) 1 country Denali Therapeutics Inc.

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