Topotecan Hydrochloride

3 trials

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3 Registered trials

0 Recruiting

2 Completed trials

3 Sponsors

14 Countries

Phase III

Phase I/II

Phase III: 2 Phase I/II: 1

Oversight events:

1 unexpected event across 1 trial

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Indications tested

Ovarian cancer 2 Fallopian tube cancer 1 Neuroblastoma 1 Medulloblastoma 1 Rhabdomyosarcoma 1 Glioblastoma 1 Peritoneal cancer index 1

Sponsors using this IMP

Incyte Corp. 1 Mural Oncology Inc. 1 Novartis Pharma AG 1

All trials

3 total

Phase 3 Study of INCB123667 Versus Investigator's Choice of Chemotherapy in Platinum Resistant Ovarian Cancer With Cyclin E1 Overexpression Pending

2025-522748-42-00 Phase III 8 countries Incyte Corp.
Study to assess safety and identify dose of ribociclib in combination of temozolomide and topotecan (TOTEM) in patients (12 months – 21 year… Ended

2024-512095-35-00 Phase I/II 7 countries Novartis Pharma AG
Study of Nemvaleukin Alfa in Combination with Pembrolizumab Versus Investigator's Choice Chemotherapy in Patients with Platinum-Resistant Ep… Ended

2024-513230-38-00 Phase III 10 countries Mural Oncology Inc.

Showing 1–3 of 3 trials

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