Trabectedin — Drug Intelligence | 8 EU Trials

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8 Registered trials

6 Recruiting

1 Completed trials

5 Sponsors

5 Countries

Phase III

Phase II

Phase I/II

Phase III: 1 Phase II: 6 Phase I/II: 1

Oversight events:

3 temporary halts across 1 trial

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Indications tested

Dedifferentiated liposarcoma 1 Pleomorphic liposarcoma 1 Myxoid liposarcoma 1 Leiomyosarcoma metastatic 1 Leiomyosarcoma 1 Round cell liposarcoma 1

Sponsors using this IMP

Asoc Grupo Espanol De Investigacion En Sarcomas 2 Italian Sarcoma Group 2 Unicancer 2 Fondazione Policlinico Universitario Agostino Gemelli IRCCS 1 Intensity Therapeutics Inc. 1

All trials

8 total

Phase I-II prospective trial, multicenter, open label, exploring the combination of Trabectedin plus RAdiotherapy in Soft Tissue Sarcoma pat… Pending

2024-518199-30-00 Phase I/II 3 countries Asoc Grupo Espanol De Investigacion En Sarcomas
A study to investigate efficacy and safety of INT230-6 compared with US standard of care in participants aged ≥ 18 years old with metastatic… Recruiting

2024-512423-36-00 Phase III 5 countries Intensity Therapeutics Inc.
Interest of post-operative chemotherapy in patients with localized uterine leiomyosarcoma suspected to have a high-risk of relapse based on … Recruiting

2023-506350-21-00 Phase II 1 country Unicancer
Immunotherapy with dostarlimab for locally advanced or metastatic cancer (non-colorectal/non-endometrial) with tumor dMMR/MSI Recruiting

2023-505298-34-00 Phase II 1 country Unicancer
Clinical trial of trabectedin and low-dose radiation therapy in advanced/metastatic sarcomas Recruiting

2023-509215-81-00 Phase II 1 country Asoc Grupo Espanol De Investigacion En Sarcomas
A Randomized & Observational phase II trial comparing the activity of TrabectedIn vs gemCitabine in patients with metastatic or locally adva… Recruiting

2024-513820-40-00 Phase II 1 country Italian Sarcoma Group
Phase II study on trabectedin in adults and young adults HEY1-NOCA2 positive skeletal and extra-skeletal mesenchymal chondrosarcoma (MCS) Recruiting

2024-514319-85-00 Phase II 1 country Italian Sarcoma Group
RECHALLENGE WITH PEGYLATED LIPOSOMAL DOXORUBICIN ADDED TO TRABECTEDIN IN RECURRENT OVARIAN CANCER: A MULTICENTER, PROSPECTIVE TRIAL.(REPRAB … Ended

2024-518847-40-00 Phase II 1 country Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Showing 1–8 of 8 trials

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