EGFR gene mutation

6 trials 3 recruiting MedDRA PT
6 Registered trials
3 Recruiting
5 Unique sponsors
10 Unique IMPs
4 Commercial trials
Drug classes (ATC)
ATC code not specified 5
L Oncology (ATC L) 2
Mechanism of action (INN-stem analysis)
Unknown / small molecule 3 substances
Kinase inhibitor 2 substances
Platinum compound 2 substances
Checkpoint inhibitor (PD-1) 1 substance
Antimetabolite 1 substance
Antibody-drug conjugate (ADC) 1 substance
Phase III: 1 Phase II: 3 Phase I (Other): 3

Filter these 6 trials by country, sponsor, date range and more.

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Show: 6 trials

Phase III

1 trial
  • Bayer AG Commercial
    3-(3-CHLORO-2-METHOXYANILINO)-2-{3-[(2S)-1,4-DIOXAN-2-YLMETHOXY]PYRIDIN-4-YL}-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE; BAY 2927088; CARBOPLATIN; CISPLATIN; PEMBROLIZUMAB; PEMETREXED; SEVABERTINIB
    2024-511319-91-00 18 countries 2024 n=174
    Recruiting

Phase II

3 trials
  • Bayer Consumer Care AG Commercial
    3-(3-CHLORO-2-METHOXYANILINO)-2-{3-[(2S)-1,4-DIOXAN-2-YLMETHOXY]PYRIDIN-4-YL}-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE; BAY 2927088; SEVABERTINIB
    2024-517419-62-00 4 countries 2025 n=37
    Recruiting
  • Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting Academic
    PATRITUMAB DERUXTECAN; ZIRCONIUM (89ZR) PATRITUMAB DERUXTECAN
    2023-508233-14-00 1 country 2025 n=16
    Recruiting
  • Vestre Viken HF Academic
    OSIMERTINIB
    2024-513881-20-00 3 countries 2018 n=96
    Ended

Phase I (Other)

3 trials
  • Bayer AG Commercial
    IMP not specified
    2022-502771-38-00 1 country 2024 n=8
    Ended
  • TOLREMO therapeutics AG Commercial
    IMP not specified
    2024-519071-25-00 1 country n=40
    Pending
  • Bayer AG Academic
    IMP not specified
    2022-502771-38-00 1 country 2024 n=8
    Ended
Sponsor activity
SponsorTypeTrialsPhasesRecruiting
Bayer AG Commercial 3 Phase I (Other), Phase III 1
TOLREMO therapeutics AG Commercial 1 Phase I (Other) 0
Bayer Consumer Care AG Commercial 1 Phase II 1
Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting Academic 1 Phase II 1
Vestre Viken HF Academic 1 Phase II 0
New trials by year
2024
3
2025
2
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