14
Registered trials
3
Recruiting
12
Unique sponsors
20
Unique IMPs
13
Commercial trials
Drug classes (ATC)
—
ATC code not specified
8
L
Oncology (ATC L)
5
N
Neurology/Psychiatry (ATC N)
1
Mechanism of action (INN-stem analysis)
Unknown / small molecule
9 substances
Kinase inhibitor
4 substances
Checkpoint inhibitor (PD-1)
2 substances
Platinum compound
2 substances
Checkpoint inhibitor (CTLA-4)
1 substance
Antimetabolite
1 substance
Checkpoint inhibitor (PD-L1)
1 substance
Phase III:
1
Phase II/III:
1
Phase II:
6
Phase I/II:
3
Phase I:
1
Phase I (Other):
1
Phase I (First in Human):
1
Phase III
1 trial-
EndedXcovery Holding Co. LLC CommercialCRIZOTINIB; X-396
Phase II/III
1 trial-
RecruitingBristol-Myers Squibb Services Unlimited Company Commercial2-[4-[4-(AMINOMETHYL)-1-OXO-2H-PHTHALAZIN-6-YL]-2-METHYLPYRAZOL-3-YL]-4-CHLORO-6-CYCLOPROPYLOXY-3-FLUOROBENZONITRILE
Phase II
6 trials-
EndedAnheart Therapeutics Inc. CommercialTALETRECTINIB
-
EndedAstraZeneca AB CommercialOSIMERTINIB; SAVOLITINIB
-
EndedBristol-Myers Squibb Services Unlimited Company CommercialBMS-986315; NIVOLUMAB
-
EndedBristol-Myers Squibb Services Unlimited Company CommercialIPILIMUMAB; NIVOLUMAB
-
EndedCelgene Corp. CommercialAZACITIDINE
-
EndedCentre Francois Baclesse AcademicATEZOLIZUMAB; CARBOPLATIN; CISPLATIN
Phase I/II
3 trials-
RecruitingBioNTech SE CommercialBNT326; BNT327
-
EndedCullinan Pearl Corp. CommercialCLN-081
-
EndedIncyte Corp. CommercialADAGRASIB; INCB099280
Phase I
1 trial-
EndedAbbVie Deutschland GmbH & Co. KG CommercialIMP not specified
Phase I (Other)
1 trial-
RecruitingSystimmune Inc. CommercialIMP not specified
Phase I (First in Human)
1 trial-
EndedAchilles Therapeutics UK Limited CommercialATL001; PEMBROLIZUMAB
Sponsor activity
| Sponsor | Type | Trials | Phases | Recruiting |
|---|---|---|---|---|
| Bristol-Myers Squibb Services Unlimited Company | Commercial | 3 | Phase II/III, Phase II | 1 |
| AbbVie Deutschland GmbH & Co. KG | Commercial | 1 | Phase I | 0 |
| Systimmune Inc. | Commercial | 1 | Phase I (Other) | 1 |
| Anheart Therapeutics Inc. | Commercial | 1 | Phase II | 0 |
| AstraZeneca AB | Commercial | 1 | Phase II | 0 |
| Celgene Corp. | Commercial | 1 | Phase II | 0 |
| Xcovery Holding Co. LLC | Commercial | 1 | Phase III | 0 |
| Achilles Therapeutics UK Limited | Commercial | 1 | Phase I (First in Human) | 0 |
| BioNTech SE | Commercial | 1 | Phase I/II | 1 |
| Cullinan Pearl Corp. | Commercial | 1 | Phase I/II | 0 |
| Incyte Corp. | Commercial | 1 | Phase I/II | 0 |
| Centre Francois Baclesse | Academic | 1 | Phase II | 0 |
New trials by year
2019
2
2020
1
2021
2
2022
1
2024
1
2025
3
2026
1