15
Registered trials
7
Recruiting
12
Unique sponsors
24
Unique IMPs
10
Commercial trials
Drug classes (ATC)
L
Oncology (ATC L)
10
—
ATC code not specified
5
Mechanism of action (INN-stem analysis)
Unknown / small molecule
6 substances
PARP inhibitor
4 substances
Monoclonal antibody (tumor, humanized)
3 substances
Checkpoint inhibitor (PD-1)
2 substances
Kinase inhibitor
2 substances
Platinum compound
1 substance
Anthracycline
1 substance
Antimetabolite
1 substance
Taxane
1 substance
Monoclonal antibody
1 substance
Monoclonal antibody (rat)
1 substance
Monoclonal antibody (immune)
1 substance
Phase III:
3
Phase II:
6
Phase III/IV:
1
Phase IV:
1
Phase I (Other):
1
Phase I (First in Human):
3
Phase III
3 trials-
EndedF. Hoffmann-La Roche AG CommercialPERTUZUMAB; TRASTUZUMAB
-
RecruitingMerck Sharp & Dohme LLC CommercialSACITUZUMAB TIRUMOTECAN
-
RecruitingIRCCS Istituto Nazionale Tumori Fondazione Pascale AcademicOLAPARIB
Phase II
6 trials-
EndedAGO Research GmbH CommercialCARBOPLATIN; DOXORUBICIN HYDROCHLORIDE, LIPOSOMAL; GEMCITABINE HYDROCHLORIDE; NIRAPARIB TOSILATE MONOHYDRATE; OLAPARIB; PACLITAXEL; RUCAPARIB
-
EndedUSWM Ct LLC CommercialAUTOLOGOUS T CELLS EXPRESSING CD8A AND A T-CELL RECEPTOR TARGETING MAGE-A4; NIVOLUMAB
-
EndedVerastem Inc. CommercialAVUTOMETINIB; DEFACTINIB
-
EndedAsso De Recherche Cancers Gynecologiques AcademicMPS-112, MPS-106, MPS-213, MPS-102, MPS-216, MPS-103, MPS-215, MPS-214, D-ALA-LYS-CHA-VAL-ALA-ALA-TRP-THR-LEU-LYS-ALA-ALA-D-ALA, MPS-200; PEMBROLIZUMAB
-
RecruitingIRCCS Istituto Nazionale Tumori Fondazione Pascale AcademicOLAPARIB
-
EndedNord Ostdeutsche Gesellschaft Fuer Gynaekologische Onkologie e.V. AcademicPEMBROLIZUMAB
Phase III/IV
1 trial-
EndedMerck Sharp & Dohme LLC CommercialPEMBROLIZUMAB
Phase IV
1 trial-
RecruitingRita Fior AcademicIMP not specified
Phase I (Other)
1 trial-
EndedK-Group Beta Inc. CommercialAZENOSERTIB; NIRAPARIB
Phase I (First in Human)
3 trials-
RecruitingDaiichi Sankyo Inc. CommercialDS-3939A
-
RecruitingRegeneron Pharmaceuticals Inc. CommercialCEMIPLIMAB, FIANLIMAB; REGN5668; SARILUMAB; UBAMATAMAB
-
RecruitingRegeneron Pharmaceuticals Inc. CommercialCEMIPLIMAB; SARILUMAB; UBAMATAMAB
Sponsor activity
| Sponsor | Type | Trials | Phases | Recruiting |
|---|---|---|---|---|
| Merck Sharp & Dohme LLC | Commercial | 2 | Phase III/IV, Phase III | 1 |
| Regeneron Pharmaceuticals Inc. | Commercial | 2 | Phase I (First in Human) | 2 |
| IRCCS Istituto Nazionale Tumori Fondazione Pascale | Academic | 2 | Phase II, Phase III | 2 |
| K-Group Beta Inc. | Commercial | 1 | Phase I (Other) | 0 |
| AGO Research GmbH | Commercial | 1 | Phase II | 0 |
| USWM Ct LLC | Commercial | 1 | Phase II | 0 |
| Verastem Inc. | Commercial | 1 | Phase II | 0 |
| F. Hoffmann-La Roche AG | Commercial | 1 | Phase III | 0 |
| Daiichi Sankyo Inc. | Commercial | 1 | Phase I (First in Human) | 1 |
| Asso De Recherche Cancers Gynecologiques | Academic | 1 | Phase II | 0 |
| Nord Ostdeutsche Gesellschaft Fuer Gynaekologische Onkologie e.V. | Academic | 1 | Phase II | 0 |
| Rita Fior | Academic | 1 | Phase IV | 1 |
New trials by year
2020
1
2021
4
2022
2
2023
2
2025
5