Phase II/III (Integrated)

392 trials 186 recruiting

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Effect of Allogenic Ex-vivo Expanded Bone Marrow Derived Mesenchymal Stem Cells on Knee Osteoarthritis – A Randomized Controlled Trial Not authorised

2023-503974-19-00 Osteoarthritis in knee joint
A 2-stage, Adaptive, Randomised, Double-blind, Placebo-controlled, Multicentre Study to Evaluate Dose and Treatment Effect of Pentosan Polys… Not authorised

2022-500228-31-00 Knee osteoarthritis pain
Baricitinib for treating hospital-acquired pneumonia in critically ill patients with a proinflammatory phenotype, an international phase II … Not authorised

2023-503480-42-00 Hospital-acquired pneumonia
Study BT8009-230 in Subjects with Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2) Not authorised

2023-504231-41-00 Locally advanced or metastatic urothelial cancer
Short title: TOTT: Tailoring Obesity Treatment Trial Not authorised

2024-510802-10-00 Obesity (BMI ≧ 30kg/m2)
IDE196 (DAROVASERTIB) IN COMBINATION WITH CRIZOTINIB VERSUS INVESTIGATOR’S CHOICE OF TREATMENT AS FIRST-LINE THERAPY IN HLA-A2 NEGATIVE META… Not authorised

2023-506686-66-00 HLA-A2 negative metastatic uveal melanoma
IVIGSeN Pending

2022-501717-31-00 Idiopathic painful small fiber neuropathy or sensory ne
68Ga-FAPI-46 PET for imaging of gastrointestinal cancers: A prospective interventional single-arm clinical trial (FAPI-PET-GI) Pending

2023-506030-70-00 Gastrointestinal cancers (including hepatocellular carc
SCARR : « Allogenic Umbilical Cord Mesenchymal Stromal Cells for the treatment of chronic renal (cABMR) graft rejection » Pending

2023-506598-36-00 Adult Patients kidney transplant recipients who have de
GBS-NN/NN2 (50 μg of each fusion protein [GBS-NN and GBS-NN2] in combination with 500 μg Aluminum as Alhydrogel®) given with and without the… Pending

2023-508563-73-00 Prevention of Group B streptococcus infection
A study to investigate efficacy of RP2 with nivolumab compared to ipilimumab with nivolumab in adult patients with advanced uveal melanoma n… Pending

2023-508784-68-00 metastatic uveal melanoma
Effect of Sildenafil in association to Hypothermia on survival without brain lesions In term Neonates with hypoxic-ischemic Encephalopathy: … Pending

2023-508928-35-00 Hypoxic ischemic encephalopathy
Study of Oral Weekly GS-1720 and GS-4182 Versus Biktarvy in People With HIV-1 Who Are Virologically Suppressed Pending

2024-511054-50-00 HIV-1 Infection
SIOP PNET 5 medulloblastoma Pending

2024-513724-42-00 Medulloblastoma
TOTAL NEOADJUVANT TREATMENT WITHOUT SURGERY FOR LOCALLY ADVANCED RECTAL CANCER: PROSPECTIVE CLINICAL TRIAL TO ASSESS TUMOR COMPLETE RESPONSE… Pending

2024-515225-28-00 Adenocarcinoma of the medium/lower rectum in Stage II (
Apixaban/rivaroxaban Versus Aspirin for primary prevention of thrombo-embolic complications in JAK2V617F-positive myeloproliferative neoplas… Pending

2024-515362-13-00 Philadelphia-negative myeloproliferative neoplasms are
A randomized, double-blinded, placebo-controlled, multicenter, phase II/III efficacy and safety study of oral TherO2-01S22 as add-on therapy… Pending

2024-516576-15-00 metastatic breast cancer
Assessment of the impairment of the serotoninergic system during the prodromal phase of Parkinson’s disease in SNCA mutation carriers by PET… Pending

2024-516610-38-00 Parkinson's disease
A Study of Treatments for the Prevention of Disease Progression in Individuals at Risk for or With Early Onset Alzheimer’s Disease Caused by… Pending

2024-517187-36-01 Dominantly Inherited Alzheimer’s Disease (DIAD)
Durability of Immunity induced by the Ebolavirus Vaccine VSV-EBOV and Assessment of a Booster Dose for Pre-Exposure Prophylaxis in Individua… Pending

2024-517352-35-00 Ebola virus infection
A clinical trial to assess the safety of EXV-802 and EXV-801 and how well they work to reduce agitation symptoms in people with Alzheimer's … Pending

2024-517388-22-00 Agitation in Alzheimer's Disease Dementia
Phase II-III study to assess the efficacy and safety of sublingual immunotherapy in patients suffering from birch pollen allergy Pending

2024-517520-19-00 Patients with moderate-to-severe allergic rhinitis / rh
Chemo-immunotherapy before and after surgery for peritoneal metastases of large bowel cancer. Pending

2024-518570-13-00 Resectable peritoneal metastases of a colorectal origin
Pilot study of the pharmacokinetic profile of subcutaneous versus intravenous paracetamol in palliative patients Pending

2024-518795-31-00 Adult patients (> 18 years of age) undergoing palliativ