Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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A randomised non-inferiority trial with nested PK to assess DTG/3TC fixed dose formulations for the maintenance of virological suppression i… Ended

2024-520388-15-00 HIV-infected 2023-06-30
Evaluation of Long-Term Safety and Efficacy of Apitegromab in Patients with Spinal Muscular Atrophy (a genetic condition that causes muscle … Ended

2024-511654-42-00 Spinal Muscular Atrophy (SMA) 2023-06-28
A STUDY TO INVESTIGATE THE SAFETY AND EFFECTIVENESS OF FURMONERTINIB COMPARED TO PLATINUM-BASED CHEMOTHERAPY FOR PATIENTS WITH NON-SMALL CEL… Ended

2022-502977-41-00 Non-Small Cell Lung Cancer 2023-06-23
A Study to Examine the Efficacy and Safety of ZX008 in Subjects with CDKL5 Deficiency Disorder Ended

2023-506269-78-00 CDKL5 Deficiency disorder 2023-06-20
A study to test trimodulin in adult hospitalized patients with severe pneumonia Ended

2022-501352-28-00 Severe community-acquired pneumonia (sCAP) 2023-06-07
Phase 3 Clinical Trial of Gedatolisib in Patients with HR Positive, HER2 Negative Advanced or Metastatic Breast Cancer (VIKTORIA-1) Ended

2022-502145-10-00 Hormone Receptor (HR)-Positive, Human Epidermal Growth 2023-06-06
Efficacy and Safety of Deucravacitinib Compared with Placebo in Participants with Active SLE (POETYK SLE-2) Ended

2022-500700-22-00 Active Systemic Lupus Erythematosus (SLE) 2023-05-25
A phase 3 clinical trial of a new combination treatment, domvanalimab and zimberelimab, plus chemotherapy, for people with an upper gastroin… Ended

2023-507522-16-00 Metastatic Esophageal or Gastric Cancer 2023-05-22
A research study looking at how safe somapacitan is and how well it works in children who need help to grow – REAL 9 Ended

2022-501055-87-01 Noonan syndrome 2023-05-18
A study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan in Patients with C3 Glomerulopathy or Immune-Complex Membranoprolifer… Ended

2023-504625-39-00 C3 glomerulopathy (C3G) or immune complex membranoproli 2023-05-18
Phase 3 study to evaluate ianalumab on top of standard-of-care therapy in patients with systemic lupus erythematosus (SIRIUS-SLE 2) Ended

2023-508499-12-00 Systemic Lupus Erythematosus 2023-05-17
A randomised, phase 3 trial comparing 3-weekly docetaxel 75 mg/m2 versus 2-weekly Docetaxel 50 mg/m2 in combination with Darolutamide + ADT … Ended

2022-502634-52-00 prostate cancer 2023-05-16
OCEAN(a)-Outcomes – Olpasiran trials of Cardiovascular Events And LipoproteiN(a) reduction – Outcomes trial Ended

2022-501608-85-00 Cardiovascular disease (atherosclerotic cardiovascular 2023-05-09
HERMES – A research study to look at how ziltivekimab works compared to placebo in people with heart failure and inflammation. Ended

2022-501939-16-00 Heart failure (HF) with mildly reduced ejection fractio 2023-05-09
A research study looking at long-term treatment with Mim8 in people with haemophilia A (FRONTIER 4) Ended

2022-502215-10-00 Haemophilia A (with or without inhibitors) 2023-05-04
An early access study of ivosidenib in patients with a pretreated locally advanced or metastatic cholangiocarcinoma Ended

2022-501463-40-01 Locally Advanced or Metastatic Cholangiocarcinoma 2023-05-03
TEMP-PREVENT Ended

2024-512133-33-00 Pseudoxanthoma Elasticum 2023-04-26
Pramipexole in depression - a follow-up study Ended

2022-502270-17-00 Depression 2023-04-21
A clinical trial of relacorilant (study drug) with nab-paclitaxel in patients with ovarian, fallopian tube or peritoneal cancer Ended

2024-514080-25-00 Advanced, Platinum-Resistant, High-Grade Epithelial Ova 2023-04-21
LOGGIC/FIREFLY-2: DAY101 vs. Standard of Care Chemotherapy in Pediatric Patients with Low-Grade Glioma Requiring First-Line Systemic Therapy Ended

2024-510742-13-00 Pediatric low-grade glioma harboring an activating RAF 2023-04-19
Clinical Study of Subcutaneous Pembrolizumab Coformulated with Hyaluronidase (MK-3475A) versus Intravenous Pembrolizumab, Given with Chemoth… Ended

2022-501506-36-00 First-line treatment of participants with metastatic no 2023-04-11
Antiviral treatment for long covid. Ended

2023-510337-29-00 Virus Diseases 2023-04-11
Anticoagulant Regimens Given to achieve thrombus regression and reduce clinical Outcomes among patients with Non device-related intra-cardia… Ended

2024-512685-33-00 intra-cardiac thrombus 2023-04-11
An Open-Label Extension Study to Evaluate Long Term Safety and Efficacy of Tildrakizumab in Patients with Psoriatic Arthritis. Ended

2022-501480-41-00 Psoriatic Arthritis 2023-04-06