Institut National De La Sante Et De La Recherche Medicale — Sponsor Intelligence | 10 EU Trials

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10 Registered trials

4 Recruiting

2 Completed trials

1 Countries active

18 Unique IMPs

100% Results reported

Phase III

Phase II/III

Phase I

Phase I (Other)

Phase I (FiH)

Phase III: 2 Phase II/III: 5 Phase I: 1 Phase I (Other): 1 Phase I (FiH): 1

Oversight events:

2 temporary halts across 2 trials

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100%

2 of 2 completed trials have published summary results (EU CTR Article 37 — 12-month obligation).

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Top indications

Dementia Alzheimer's type 2 Schizophrenia 1 Parkinson's disease 1 Epidermolysis bullosa 1 Disease prodromal stage 1

Top IMPs

(1-(11C)METHYLPIPERIDIN-4-YL)METHYL 5-AMINO-6-CHLORO-1,4-BENZODIOXINE-8-CARBOXYLATE 1 3-AMINO-4-[2-[[METHYL((111C)METHYL)AMINO]METHYL]PHENYL]SULFANYLBENZONITRILE 1 AUTOLOGOUS KERATINOCYTES AND FIBROBLASTS TRANSDUCED WITH A RETROVIRAL VECTOR ENCODING COL7A1 CDNA 1 CAPMATINIB 1 CERITINIB 1 DABRAFENIB 1 DURVALUMAB 1 FLORTAUCIPIR (18F) 1 FUTIBATINIB 1 GLASDEGIB 1 LAPATINIB 1 METHYL (1R,2S,3S,5S)-8-[(E)-4-(18F)FLUORANYLBUT-2-ENYL]-3-(4-METHYLPHENYL)-8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLATE 1

All trials

10 total

Assessment of the impairment of the serotoninergic system during the prodromal phase of Parkinson’s disease in SNCA mutation carriers by PET… Pending

2024-516610-38-00 Phase II/III 1 country (1-(11C)METHYLPIPERIDIN-4-YL)METHYL 5-AMINO-6-CHLORO-1,4-BENZODIOXINE-8-CARBOXYL…
MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A MRI/TEP STUDY Pending

2024-519995-20-00 Phase II/III 1 country FLORTAUCIPIR (18F)
CIRAANO: Multimodal exploration of theater actors, memory athletes, and patients with various memory pathologies: evaluation of mnesic strat… Pending

2025-523264-21-00 Phase II/III 1 country
Phase I/II ex vivo gene therapy clinical trial for RDEB using autologous skin equivalent grafts genetically corrected with a COL7A1-encoding… Recruiting

2024-518368-10-00 Phase I (FiH) 1 country AUTOLOGOUS KERATINOCYTES AND FIBROBLASTS TRANSDUCED WITH A RETROVIRAL VECTOR ENC…
Assessment of microglial activation in patients with schizophrenia stratified for C4 complement by PET using [18F]DPA-714 Recruiting

2023-504181-38-00 Phase II/III 1 country N,N-DIETHYL-2-(2-(4-(2[(18)F]-FLUOROETHOXY)PHENYL)5,7DIMETHYLPYRAZOLO[1,5A]PYRIM…
Dopaminergic disruption induced by traumatic coma: multimodal neuroimaging approaches to characterize dopaminergic pathways abnormalities an… Recruiting

2023-504893-39-00 Phase II/III 1 country METHYL (1R,2S,3S,5S)-8-[(E)-4-(18F)FLUORANYLBUT-2-ENYL]-3-(4-METHYLPHENYL)-8-AZA…
APEDOC: The role of peripheral afferents in modulating post-stroke central pain Recruiting

2023-504676-17-00 Phase III 1 country
Evaluation of tolerance and pharmacokinetics profile of high dose favipiravir in healthy volunteers - FAVIDOSE Halted

2022-502871-49-00 Phase I (Other) 1 country
Phase I single-blind clinical trial to evaluate the safety and local immune activation of a toll-like receptor 5 agonist (FLAMOD) administer… Ended

2024-515933-14-00 Phase I 1 country
MULTISARC : MOLECULAR PROFILING OF ADVANCED SOFT-TISSUE SARCOMAS. A phase III study Ended

2024-514873-22-00 Phase III 1 country CAPMATINIB; CERITINIB; DABRAFENIB; DURVALUMAB; FUTIBATINIB; GLASDEGIB; LAPATINIB…

Showing 1–10 of 10 trials

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