Leids Universitair Medisch Centrum (LUMC) — Sponsor Intelligence | 32 EU Trials

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32 Registered trials

15 Recruiting

8 Completed trials

1 Countries active

42 Unique IMPs

100% Results reported

Phase II

Phase I/II

Phase IV

Phase III: 2 Phase II/III: 1 Phase II: 5 Phase I/II: 4 Phase III/IV: 3 Phase IV: 11 Phase I: 2 Phase I (Other): 1 Phase I (FiH): 3

100%

8 of 8 completed trials have published summary results (EU CTR Article 37 — 12-month obligation).

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Top indications

Malaria immunisation 3 Heart transplant 1 Liver transplant 1

Top IMPs

SODIUM CHLORIDE 3 PEMBROLIZUMAB 2 TIL CELLS 2 [AL[18F]F]FAPI-74 1 6QC-ICG 1 ALPHA-TOCOPHEROL 1 B/PHUKET/3073/2013 - LIKE STRAIN (B/PHUKET/3073/2013, MEDI 306444), INFLUENZA VIRUS B/AUSTRIA/1359417/2021 - LIKE STRAIN (B/AUSTRIA/1359417/2021, MEDI 355292), A/DARWIN/9/2021 (H3N2) - LIKE STRAIN (A/NORWAY/16606/2021, MEDI 355293), INFLUENZA VIRUS A/VICTORIA/4897/2022 (H1N1)PDM09 - LIKE STRAIN (A/NORWAY/31694/2022, MEDI 369815) 1 B/PHUKET/3073/2013-LIKE VIRUS (B/PHUKET/3073/2013, WILD TYPE), INFLUENZA VIRUS B/MICHIGAN/01/2021, INFLUENZA A/VICTORIA/4897/2022 IVR-238 (H1N1), INACTIVATED, INFLUENZA VIRUS A/CALIFORNIA/122/2022 SAN-022 (H3N2) STRAIN (SPLIT, INACTIVATED) 1 BEVACIZUMAB ZIRCONIUM ZR-89 1 C1 ESTERASE INHIBITOR (HUMAN) 1 CABOZANTINIB 1 DULOXETINE 1

All trials

32 total

Investigating the (autoreactive) B cell compartment in antibody-mediated autoimmune diseases in comparison with the recall Tetanus Toxoid re… Pending

2024-515312-50-00 Phase IV 1 country TETANUS TOXOID
LUMC-BOB1-B7-TCR.1 in relapsed and refractory B-cell malignancies Pending

2024-515900-38-00 Phase I (FiH) 1 country LUMC-BOB1-B7-TCR.1
NEOAC Pending

2024-516126-54-00 Phase II 1 country
CHOPIN Pending

2024-516127-14-01 Phase I (FiH) 1 country
(WHAT!) – RCT: Open-label randomized controlled trial for the effects of continuous daily use of ethinylestradiol/levonorgestrel (30/150 µg/… Pending

2024-517127-40-00 Phase III/IV 1 country ALPHA-TOCOPHEROL; ETHINYLESTRADIOL, LEVONORGESTREL
Adoptive TIL therapy in combination with chemoimmunotherapy in advanced NSCLC patients Pending

2024-517939-53-00 Phase I 1 country
A phase III trial of a De-escalated Immune-strategy During first-line treAtment in patients with metastatic non-small Cell lung cancer (NSCL… Pending

2025-520792-67-00 Phase III 1 country PEMBROLIZUMAB; PEMETREXED
OVACURE-2 Pending

2025-522659-24-00 Phase I/II 1 country TIL CELLS
Study on the effect of 6qc-ICG on the skin of healthy volunteers and in patients with breast cancer during surgeries. Pending

2025-523166-24-00 Phase I (FiH) 1 country 6QC-ICG
Late immunity following single immunization with GA2 sporozoites (GACHA) Recruiting

2025-524045-27-00 Phase I/II 1 country
CIAO@TBI Recruiting

2024-514488-24-02 Phase II 1 country C1 ESTERASE INHIBITOR (HUMAN); SODIUM CHLORIDE
(PREVENT)A Randomized, Double-blind, Placebo-controlled Trial on the Prevention of Chronic Postoperative Pain after Inguinal Hernia and Knee… Recruiting

2024-511010-21-00 Phase IV 1 country TAPENTADOL HYDROCHLORIDE
Optimization of pain management for acute renal colic in the Emergency Department – The OPTIMIZED trial Recruiting

2025-521316-19-00 Phase IV 1 country
SKIPP2: Cabozantinib Dose Skipping as an Alternative to Dose Reductions Recruiting

2025-522962-58-00 Phase II 1 country CABOZANTINIB
CO2MO Recruiting

2025-520913-29-00 Phase IV 1 country
Pneumoccocal vaccine response in patients without a spleen, vaccinated before or after spleen removal. Recruiting

2024-515363-63-00 Phase IV 1 country PNEUMOCOCCAL POLYSACCHARIDE SEROTYPE 1 CONJUGATED TO CRM197 ADSORBED ON ALUMINIU…
(Pre-BCGvacc) BCG vaccination: can pre-vaccination immune status predict outcome? Recruiting

2024-514428-18-00 Phase III/IV 1 country MYCOBACTERIUM BOVIS, DANISH STRAIN 1331; RABIES VIRUS (INACTIVATED)
Characterization of antibodies in the nose after influenza vaccination Recruiting

2024-513981-21-00 Phase IV 1 country B/PHUKET/3073/2013 - LIKE STRAIN (B/PHUKET/3073/2013, MEDI 306444), INFLUENZA VI…
(PLASTIC-3) [18F]FAPI-PET/CT and Laparoscopy in STagIng advanced gastric Cancer – a multicenter prospective study Recruiting

2024-513255-32-00 Phase II/III 1 country [AL[18F]F]FAPI-74
ACTME Recruiting

2024-516125-31-02 Phase I/II 1 country TIL CELLS; ZIRCONIUM (89ZR) CREFMIRLIMAB BERDOXAM
MCA-derived MSC therapy in renal transplant recipients Recruiting

2024-512553-25-00 Phase I (Other) 1 country
(NFPET) 89Zr-Bevacizumab PET/CT imaging in NF2 patients Recruiting

2024-512860-75-00 Phase II 1 country BEVACIZUMAB ZIRCONIUM ZR-89
DEnosumab for the treatment of FIbrous Dysplasia/McCune-Albright Syndrome in adults (DeFiD): a randomized double-blind placebo-controlled tr… Recruiting

2024-511090-30-00 Phase III/IV 1 country SODIUM CHLORIDE; SODIUM FLUORIDE (18F)
Coadministration of GA2 Sporozoites With Adjuvants (CoGA) Recruiting

2024-516488-99-00 Phase I 1 country

Showing 1–24 of 32 trials

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