Takeda Development Center Americas Inc.

• A Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-279 in Subjects With Moderate-to-Severe Plaque Psoriasis Ended
  2023-505841-22-00 Phase III 3 countries APREMILAST; APREMILAST, APREMILAST; ZASOCITINIB
• A Phase 1 Study to Assess Mass Balance, Pharmacokinetics, and Metabolism of [14C]Subasumstat in Patients With Advanced or Metastatic Solid T… Ended
  2023-503449-79-00 Phase I (Other) 1 country
• A Study About Fazirsiran in People With and Without Liver Problems. Ended
  2023-503735-17-00 Phase I (Other) 2 countries
• A Study of TAK-676 as Single Agent and TAK-676 in Combination With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors Ended
  2023-505627-30-00 Phase I (FiH) 4 countries DAZOSTINAG; PEMBROLIZUMAB
• A Phase 2b study of TAK-755 (rADAMTS13) with minimal to no plasma exchange in the treatment of patients with thrombotic thrombocytopenic Pur… Ended
  2023-507787-39-00 Phase II 5 countries APADAMTASE ALFA
• A Study to evaluate Efficacy, Safety, Tolerability and Effects of TAK-341 in the human body in patients with Multiple System Atrophy Ended
  2023-509876-40-00 Phase II 7 countries HUMAN IGG1 LAMBDA MONOCLONAL ANTIBODY AGAINST ALFA-SYNUCLEIN
• A Study of Mezagitamab in Adults With Primary Immunoglobulin A Nephropathy Receiving Stable Background Therapy Ended
  2024-516743-34-00 Phase I (Other) 2 countries
• Open-label extesnion study of soticlestat in Dravet and Lennox-Gastaut Syndromes Ended
  2022-502802-34-00 Phase III 10 countries SOTICLESTAT
• A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Ulcerative Colitis (UC) Ended
  2023-509018-12-00 Phase III 6 countries VEDOLIZUMAB
• A Phase 3 Study to Evaluate the Efficacy and Safety of Darvadstrocel in the Treatment of Complex Perianal Fistula in Pediatric Subjects with… Ended
  2023-503973-39-00 Phase III 3 countries ALLOGENEIC ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS EXPANDED
• A Clinical Study to Compare the Effectiveness and Safety of Pevonedistat, Venetoclax, and Azacitidine Versus Venetoclax Plus Azacitidine in … Ended
  2024-515424-36-00 Phase II 2 countries AZACITIDINE; PEVONEDISTAT; VENETOCLAX
• A Long-term Safety Study of a Second Treatment with Darvadstrocel for Treating Complex Perianal Fistulas in Adults with Crohn's Disease Ended
  2022-503014-23-00 Phase IV 5 countries ALLOGENEIC ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS EXPANDED
• A Phase 4 study to Assess the Safety and Efficacy of Guanfacine Hydrochloride Prolonged release (SPD503) in Children and Adolescents aged 6 … Ended
  2022-502630-71-00 Phase IV 5 countries GUANFACINE
• Open-label Follow-up Study of Soticlestat in Adults and Children with Developmental Epileptic Encephalopathies Ended
  2022-502801-13-00 Phase II 3 countries SOTICLESTAT
• An extension study to investigate how safe Vedolizumab is in child patients with Ulcerative Colitis or Crohn's Disease Ended
  2023-507766-35-00 Phase II 2 countries VEDOLIZUMAB
• A study of Iclusig (ponatinib), an oral kinase-inhibitor treatment administered, by standard dose or reduced doses, for patients with Philad… Ended
  2024-514516-27-00 Phase II 2 countries PONATINIB
• Phase 3 Frontline Therapy Trial in Patients With Advanced Classical Hodgkin Lymphoma Ended
  2023-506419-16-00 Phase III 9 countries BLEOMYCIN; BLEOMYCIN SULFATE; BRENTUXIMAB VEDOTIN; DACARBAZINE; DOXORUBICIN HYDR…

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