University Hospital Maastricht — Sponsor Intelligence | 9 EU Trials

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9 Registered trials

4 Recruiting

4 Completed trials

2 Countries active

18 Unique IMPs

100% Results reported

Phase III

Phase II

Phase IV

Phase III: 1 Phase II: 4 Phase IV: 4

Oversight events:

1 temporary halt 2 corrective measures across 2 trials

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100%

4 of 4 completed trials have published summary results (EU CTR Article 37 — 12-month obligation).

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Top indications

Corneal graft failure 1 Corneal graft rejection 1

Top IMPs

(S)-2,2',2''-(10-(2-(4-(3-((4-(2-(2-CYANO-4,4-DIFLUOROPYRROLIDIN-1-YL)-2-OXOETHYLCARBAMOYL)-QUINOLIN-6-YL)(METHYL)AMINO)-PROPYL)PIPERAZIN-1-YL)-2-OXOETHYL)-68GA-[1,4,7,10]-TETRAAZACYCLODODECANE-1,4,7-TRIYL)TRIACETATE 2 1-{6-[(4M)-4-(5-CHLORO-6-METHYL-1H -INDAZOL-4-YL)-5-METHYL-3-(1-METHYL-1H -INDAZOL-5-YL)-1H -PYRAZOL-1-YL]-2-AZASPIRO[3.3]HEPTAN-2-YL}PROP-2-EN-1-ONE 1 ACETYLCHOLINE CHLORIDE 1 CALCIPOTRIOL 1 COBICISTAT 1 DEXAMETHASONE 1 EMPAGLIFLOZIN 1 FLUDEOXYGLUCOSE (18F) 1 FLUOROMETHOLONE 1 FLUOROURACIL 1 GLYCERYL TRINITRATE 1 INSULIN ASPART 1

All trials

9 total

18F-FDG versus 68Ga-FAPI-46 as PET tracer in ER-positive breast cancer - a pilot study Not authorised

2023-508066-15-00 Phase II 1 country (S)-2,2',2''-(10-(2-(4-(3-((4-(2-(2-CYANO-4,4-DIFLUOROPYRROLIDIN-1-YL)-2-OXOETHY…
18F-FDG versus 68Ga-FAPI-46 as PET tracer in ER-positive breast cancer - a pilot study Recruiting

2023-508066-15-01 Phase II 1 country (S)-2,2',2''-(10-(2-(4-(3-((4-(2-(2-CYANO-4,4-DIFLUOROPYRROLIDIN-1-YL)-2-OXOETHY…
OPTIMISE: Optimized Immunosuppression for Corneal Transplantation: a multi-centre randomized controlled clinical trial Recruiting

2022-500109-41-00 Phase IV 2 countries DEXAMETHASONE; FLUOROMETHOLONE
OSIBOOST 2: Improving Osimertinib cost-effectiveness in Non-Small Cell Lung Cancer treatment using dose-modification and pharmacokinetic boo… Recruiting

2023-505700-35-00 Phase II 1 country COBICISTAT; OSIMERTINIB
TREASURE trial Recruiting

2022-503135-33-00 Phase IV 1 country GLYCERYL TRINITRATE; PERINDOPRIL TERT-BUTYLAMINE; VALSARTAN
Combination therapy of 5-Fluorouracil and Calcipotriol versus 5-Fluorouracil in the treatment of Actinic Keratosis: a multicentre randomized… Ended

2024-511409-42-00 Phase IV 1 country CALCIPOTRIOL; FLUOROURACIL
Xerostomia in patients with a life-limiting condition or frailty: a double-blind placebo-controlled randomized clinical trial Ended

2022-501084-41-00 Phase III 1 country
The effect of empagliflozin on peripheral microvascular dysfunction in heart failure with preserved ejection fraction Ended

2022-501682-45-00 Phase IV 1 country ACETYLCHOLINE CHLORIDE; EMPAGLIFLOZIN; INSULIN ASPART; SODIUM NITROPRUSSIDE DIHY…
STRIDER: A phase II Study evaluaTing intRacranial effIcacy of JDQ443 in patiEnts with KRAS G12C+ NSCLC and bRain metastases Ended

2023-505721-13-00 Phase II 1 country 1-{6-[(4M)-4-(5-CHLORO-6-METHYL-1H -INDAZOL-4-YL)-5-METHYL-3-(1-METHYL-1H -INDAZ…

Showing 1–9 of 9 trials

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