Hemic and Lymphatic Diseases

593 trials 238 recruiting

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Phase 3 trial of VMX-C001 vs usual pharmacological care in patients taking a FXa direct oral anticoagulant who require urgent surgery with o… Pending

2025-521632-12-00 Patients on Factor Xa inhibitor treatment needing an ur 5
A Non-Investigational Product, Multi-Center Cohort Study to Describe Long-Term Safety and Effectiveness of Giroctocogene Fitelparvovec or Fi… Pending

2025-523660-21-00 hemophilia A 5
REGN7508 in Adult Participants for Prevention of Cancer-Associated Thrombosis. Pending

2024-519298-21-00 Cancer-Associated Thrombosis (CAT). 5
Study in healthy volunteers to compare the blood levels after epoetin alfa (Blau EPO) and Erypo, administered as a single intravenous inject… Pending

2025-522244-40-00 It is used to treat symptomatic anaemia in chronic rena 3
Study in healthy male participants to compare the blood levels after epoetin alfa (Blau EPO) and Erypo, administered as multiple intravenous… Pending

2025-522246-43-00 Treatment of symptomatic anemia associated with chronic 3
A Phase I/IIa study to assess the safety and biological activity of TdT-3, an autologous TCR T-cell therapy targeting TdT, in HLA-A*02:01+ p… Pending

2024-519320-24-00 Acute lymphoblastic leukemia (ALL) or lymphoblastic lym 7
PirtobrUtinib as frontline Therapy for elderly unfit/frail patient with MAntle cell lymphoma: a phase II study of the Fondazione Italiana Li… Pending

2025-521666-10-01 Mantle Cell Lymphoma 4
A Phase 2, single arm Multicenter, Study testing Mezigdomide, Carfilzomib, and Dexamethasone (480Kd) in Participants with Relapsed or Refrac… Pending

2025-521090-14-00 Patients with relapsed/refractory symptomatic multiple 4
Daratumumab in Combination with Carfilzomib, Pomalidomide and Dexamethasone in patients with myeloma induced acute renal failure Pending

2024-514702-31-00 Multiple myeloma 4
A Single Arm, Open Label, Phase 1/2 Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients with Sickle Cell D… Pending

2024-519881-32-00 Sickle Cell Disease 9
IntReALL BCP 2020 – International Study for Treatment of Childhood Relapsed Precursor B-cell ALL 2020 Pending

2023-509392-17-00 Relapsed Acute Lymphoblastic Leukemia (ALL) 5
REGN7508 versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis after Total Knee Arthroplasty in Adult Participants Pending

2025-520479-25-00 Symptomatic Venous Thromboembolism (VTE) 5
A study testing the new drug Lisaftoclax for newly diagnosed acute myeloid leukemia(GLORA-3) Pending

2024-516436-10-00 Acute myeloid leukemia 5
Iceland Screens Treats or Prevents Multiple Myeloma (iStopMM): A nationwide phase 2 trial of patients with smoldering and active multiple my… Pending

2024-519353-11-00 Multiple Myeloma 4
Phase I, first-in-human clinical trial to evaluate safety of infusion of STAb-T19 cells: genetically modified T lymphocytes secreting αCD19x… Pending

2025-524814-27-00 Malignant B-cell neoplasms 1
An adaptive open-label multicentre phase 1/2 trial, to determine the recommended phase 2 dose of CCTx-001, and to assess safety, tolerabilit… Pending

2023-506865-71-00 Relapsed/Refractory Acute Myeloid Leukemia (AML) 7
TGD001 Treatment in Thrombotic Microangiopathies Pending

2025-523802-34-00 Immune-Mediated Thrombotic Thrombocytopenic Purpura 9
Safety of Anumigilimab (CSL324) in Adults with Sickle Cell Disease Pending

2025-521154-42-00 Sickle Cell Disease 4
Double-T - Improving outcomes in high-risk 2nd line relapsed/refractory Large B-Cell Lymphoma patients eligible for CAR-T-cell therapy with … Pending

2025-523806-34-00 relapsed/refractory Large B-Cell Lymphoma 4
Clinical study to check the Efficacy and Safety of Mitapivat in Patients with Sickle Cell Disease Pending

2024-515202-84-00 Anemia in subjects with sickle cell disease (SCD) 10
Phase Ia/Ib Study of UBX-303061 in Subjects with Relapsed/Refractory B-Cell Malignancies Pending

2023-510484-35-00 B-cell malignancies 1
MInimal residual Disease Adapted Strategy / IFM 2020-02 Pending

2024-513889-19-00 Multiple Myeloma 5
Safety and Preliminary Efficacy of CTX112 in Adult Participants with Relapsed/Refractory Hematologic Autoimmune Disease Pending

2025-523845-90-00 Relapsed/Refractory Hematologic Autoimmune Disease 3
Study PACIFIC: Fixed duration treatment with combined pirtobrutinib and short course immuno-chemotherapy in fit patients with previously unt… Pending

2025-521199-80-00 Patients with previously untreated symptomatic chronic 4