Musculoskeletal and Neural Physiological Phenomena

37 trials 14 recruiting

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Exploratory study on the effect of Rimonabant on hand function in patients with spinal cord injury (RIMOHANDOPEN) Recruiting

2025-524279-22-00 Spinal cord injury 9 2026-05-22
A study of the safety, tolerability, pharmacokinetics and preliminary efficacy of TNV108 in healthy adults and patients with diabetic periph… Recruiting

2025-524258-32-00 Diabetic Peripheral Neuropathy (DPN) 1 2026-03-02
A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy Recruiting

2024-520130-29-00 Spinal Muscular Atrophy 4 2025-12-17
An Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of Once Daily Mexiletine PR in Patients with Myotonic Dystrophy … Recruiting

2024-511178-66-00 Myotonic Dystrophy type 1 and type 2 (DM1/DM2) 5 2025-09-12
An Open-Label, Randomized, Cross-Over Study to Investigate the Efficacy and Safety of Mexiletine PR compared to Mexiletine IR in Patients wi… Recruiting

2024-514970-27-00 Non-Dystrophic Myotonias (NDM) 5 2025-09-03
Blocage de l'interféron-ɣ par le ruxolitinib pour le traitement de la myosite à inclusion : un essai de phase IIb Recruiting

2023-507666-32-00 Inclusion body Myositis 4 2025-05-27
STROKE-POC Recruiting

2024-510866-18-00 Spasticity after Stroke 4 2025-02-21
Frozen Shoulder Treatment with IA Corticosteroid Injection and Suprascapular Nerve Block Recruiting

2024-513057-78-00 Adhesive Capsulitis 6 2025-02-02
Dopaminergic disruption induced by traumatic coma: multimodal neuroimaging approaches to characterize dopaminergic pathways abnormalities an… Recruiting

2023-504893-39-00 Comatose Traumatic Brain Injury patients 10 2025-01-14
A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Investigate the Efficacy and Safety of Once Daily Mexiletine PR During… Recruiting

2024-511179-13-00 Myotonic Dystrophy type 1 and type 2 (DM1/DM2) 5 2025-01-13
A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared … Recruiting

2023-504022-19-01 Polymyositis or dermatomyositis according to 2017 EULAR 5 2024-12-13
What laxatives after hip surgery? Recruiting

2024-513871-42-00 Hip fracture 6 2024-10-01
Pragmatic clinical trial to assess the utility of SLCO1B1, ABCG2, and CYP2C9 preemtive genotyping and pharmacogenetics training on the incid… Recruiting

2023-506814-31-01 Cardiovascular risk which needs primary or secundary pr 6 2024-06-25
Antibiotic Impregnated Bone Graft to reduce infection in hip replacement - the ABOGRAFT trial Recruiting

2024-510921-25-00 Prosthetic Joint Infection 4 2022-03-18
Prospective, randomized, blinded, comparative study between botulinum toxin and topical capsaicin in the treatment of postmastectomy syndrom… Ended

2024-513609-29-01 Postmastectomy Syndrome 6 2025-03-10
Exploratory study of the expression of the serotonergic 5-HT4 receptor in Parkinson's disease Ended

2022-503089-57-00 Parkinson disease 10 2023-09-18
A multicenter, open-label, controlled study to investigate the effect of either LF111 or Drospirenone chewable tablets on bone mineral densi… Ended

2024-512347-23-00 Oral contraception 6 2022-08-22
Capivasertib + Abiraterone as Treatment for Patients with Metastatic Hormone-sensitive Prostate Cancer Characterised by PTEN deficiency (CAP… Ended

2023-504998-20-00 Metastatic Hormone-sensitive Prostate Cancer Characteri 5 2020-09-18
An Extension Study to Evaluate the Efficacy and Safety of BMN 111 in Children With Achondroplasia Ended

2023-508864-31-00 Achondroplasia 5 2019-04-03
Prevention of agitation and pain after anaesthesia in children less than or equal to 1 year Halted

2024-520075-28-01 Emergence agitation after anaesthesia 4 2021-10-22
A study to compare the absorption of two tablet strengths with the absorption of a solution. Ended

2024-519835-41-00 Parkinson's Disease 2 2025-02-28
A Phase 1, randomized, double blind, single center, placebo controlled, single escalating weight-adjusted dose, safety study of HI-6 dimethy… Ended

2023-509020-17-00 Treatment of patients poisoned with organophosphorus co 1 2024-11-25
A study of the safety, absorption and effects of investigational drug ARV-102 in patients with Parkinson's disease. Ended

2024-516888-84-00 Parkinson's disease. 3 2024-11-12
A Single Dose, Fasting state, Crossover Replicate Bioequivalence Study of Naproxen 500 mg/Esomeprazole 20 mg, modified-release tablets (Anti… Ended

2024-515662-14-00 healthy subjects 2 2024-10-31