Neoplasms

3,817 trials 1,526 recruiting

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A Phase III, Randomized, Open-label, Clinical Trial to Compare Pembrolizumab with Brentuximab Vedotin in Subjects with Relapsed or Refractor… Ended

2022-500400-22-00 Hodgkin lymphoma 5 2016-06-23
"A study to learn how well the drug larotrectinib works in adults with different solid cancers with a change in the genes called NTRK fusion… Ended

2022-502667-38-00 Solid tumors harboring NTRK fusion 4 2016-06-20
A study of nivolumab or placebo in patients following removal of their esophageal or gastroesophageal junction cancer. Ended

2023-509360-24-00 Subjects with resected adenocarcinoma or squamous cell 5 2016-06-16
Adjuvant Treatment for High-risk Triple Negative Breast Cancer Patients With the Anti-PD-l1 Antibody Avelumab (A-Brave) Ended

2024-514515-10-00 Breast Cancer 5 2016-06-16
Phase I/II, Multicenter, Open-label, Clinical and Pharmacokinetic Study of Lurbinectedin in Combination with Irinotecan in Pretreated Patien… Ended

2024-515394-10-00 Selected Advanced Solid Tumors 9 2016-04-26
Treatment of neuroendocrine neoplasms with genetically modified adenovirus Ended

2024-517654-10-00 Neuroendocrine neoplasms (NENs) is a heterogeneous grou 1 2016-03-15
Pembrolizumab (MK-3475) and pembrolizumab in combination with other investigational agents in high risk NMIBC patients unresponsive to BCG Ended

2022-502526-41-00 Non-Muscle Invasive Bladder Cancer (NMIBC) 4 2016-03-15
Clinical trial to compare the efficacy and tolerability of fulvestrant (FaslodexTM) 500mg with placebo versus fulvestrant (FaslodexTM) 500mg… Ended

2024-516132-10-00 Metastatic breast cancer 4 2016-02-05
Study of First Line MEDI4736 with or without Tremelimumab versus Standard of Care Chemotherapy in Advanced Unresectable Urothelial Cancer. Ended

2024-513399-17-00 Adult patients (age ≥18 years) with histologically or c 5 2015-12-11
A clinical trial to evaluate if CC-486 plus pembrolizumab works and is safe in patients with advanced or metastatic non-small cell lung canc… Ended

2024-513405-31-00 Second-line treatment of locally advanced or metastatic 4 2015-12-10
A randomized, phase 3 trial with anti-PD-1 monoclonal antibody pembrolizumab (MK-3475) versus placebo for patients with early stage NSCLC af… Ended

2023-509137-39-00 Stage IB (T ≥ 4 cm), II and IIIA NSCLC 5 2015-11-06
A phase I/II trial of Obinutuzumab, ABT-199 (GDC-0199) plus Ibrutinib in Relapsed / Refractory Mantle Cell Lymphoma patients (OAsIs) Ended

2024-516750-21-00 Patients with relapsed / refractory Mantle Cell Lymphom 9 2015-10-14
Combined antitumor therapy with ex vivo manipulated dendritic cells producing interleukin-12 in children, adolescents and young adults with … Ended

2024-516613-21-00 Progressive, recurrent or primarily metastatic high-ris 9 2015-09-10
A Trial to See the Effects of ACP-196 (the test drug) in Patients who have Mantle Cell Lymphoma Ended

2023-509352-34-00 Mantle Cell Lymphoma 4 2015-06-18
Study is designed to assess the safety and tolerability of ceralasertib at increasing doses in combination with other anti-cancer treatment … Ended

2023-505006-41-00 QT interval prolongation 1 2015-05-11
A Study of Ramucirumab (LY3009806) in Combination With Erlotinib in Previously Untreated Participants With EGFR Mutation-Positive Metastatic… Ended

2024-514269-20-00 Metastatic Non-Small Cell Lung Cancer 5 2015-05-06
Safety Study of Anti-LAG-3 With and Without Anti-PD-1 in the Treatment of Solid Tumors Ended

2023-508067-70-00 Neoplasms by site 9 2015-04-15
A Phase III Prospective Double Blind Placebo Controlled Randomized Study of Adjuvant MEDI4736 in Completely Resected Non-Small Cell Lung Can… Ended

2024-517856-36-00 Completely resected primary stage IB (≥ 4cm), II and II 5 2015-03-09
Randomised phase 3 trial of enzalutamide in androgen deprivation therapy with radiation therapy for high risk, clinically localised, prostat… Ended

2024-514808-13-00 Localised prostate cancer at high risk of recurrence 5 2015-03-06
The study evaluates the efficacy of the therapy of Mistletoe Extract in patients with superficial bladder cancer. There fore the Mistletoe E… Ended

2023-503718-66-00 Male and female patients aged ≥ 18 to ≤ 85 years with a 5 2015-02-11
Multicenter trial with carfilzomib combined with lenalidomide or cyclophopshamide with or without autologous transplant in newly diagnosed m… Ended

2024-516630-35-01 NEWLY DIAGNOSED MULTIPLE MYELOMA (MM) PATIENTS ELEGIBLE 4 2015-01-12
A Phase 3 Study of Nivolumab plus Ipilimumab Versus Sunitinib in untreated Subjects with Advanced or Metastatic Renal Cell Carcinoma (RCC) Ended

2023-504761-23-00 Advanced or metastatic renal cell carcinoma 5 2014-11-19
A Phase II Study of MEDI4736 in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer Ended

2024-512379-10-00 Locally Advanced or Metastatic Non-Small Cell Lung Canc 4 2014-09-23
A Study Comparing Alectinib With Crizotinib in Treatment-Naive Anaplastic Lymphoma Kinase-Positive Advanced Non-Small Cell Lung Cancer Parti… Ended

2023-506859-13-00 Anaplastic lymphoma kinase (ALK)-positive non-small cel 5 2014-09-09