Neoplasms

3,817 trials 1,526 recruiting

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Trial evaluating the efficacy and the safety of FOLFIRINOX3 treatment in patients with unresectable locally advanced or metastatic pancreati… Recruiting

2023-505889-29-01 Patients with unresectable locally advanced or metastat 4 2024-02-01
Pan-tumor neoadjuvant basket study of immune check-point inhibition and novel IO combinations (NEOASIS) Recruiting

2023-505756-21-00 dMMR tumors consisting of but not limited to; Colorecta 4 2024-01-26
A Phase 1/2 study of Enzomenib (DSP-5336) in Adult Patients with Acute leukemia Recruiting

2022-502741-10-00 Acute Leukemia with Mixed Lineage Leukemia (MLL)-rearra 7 2024-01-26
Clinical and translational controlled study of Perampanel treatment around Surgery in patients with progressive glioblastoma (PerSurge) Recruiting

2023-503938-52-00 Progressive Glioblastoma 4 2024-01-26
A study to Evaluate Efficacy and Safety of Giredestrant Compared with Fulvestrant (plus a CDK4/6 inhibitor), in Participants with ER+ HER2-N… Recruiting

2022-502980-39-00 Estrogen receptor (ER)-positive, HER2-negative advanced 5 2024-01-25
IMPlementing geriatric assessment for dose Optimization of CDK 4/6-inhibitors in older bReasT cAncer patieNTs – a pragmatic randomized-contr… Recruiting

2023-506620-87-00 Advanced Breast Cancer in older patients 11 2024-01-25
Multicenter Phase 2 study to evaluate the efficacy and safety of Cetuximab in combination with Encorafenib plus Binimetinib as induction tre… Recruiting

2022-502413-29-00 BRAF V600E mutated and microsatellite stable (MSS) adva 4 2024-01-22
FIRST IN-HUMAN STUDY EVALUATING THE EFFECT OF VARIOUS DOSES OF ODM-212 IN SUBJECTS WITH SELECTED ADVANCED SOLID TUMOURS Recruiting

2022-503061-29-00 Neoplasms benign malignant and unspecified (incl cysts 7 2024-01-22
Discontinuation of CDK4/6 inhibitors in patients with metastatic HR positive, HER2 negative breast cancer with durable disease control: A ra… Recruiting

2023-504141-31-00 Metastatic HR positive, HER2 negative breast cancer 4 2024-01-17
A study to investigate the effect of adding cobicistat to venetoclax and azacitidine in patients with acute myeloid leukemia (AML) who are i… Recruiting

2023-505379-61-00 Acute Myeloid Leukaemia 4 2024-01-17
Phase 2a non-commercial and non-randomized intervention study evaluating the efficacy of crizotinib in the treatment of children with severe… Recruiting

2024-516607-16-00 Neurofibromatosis type 2 is a genetically determined pr 4 2024-01-17
AGNOSTIC THERAPY IN A PHASE II, MULTICENTER, SINGLE-ARM STUDY IN FIRST-LINE TREATMENT OF DURVALUMAB (MEDI 4736) IN ASSOCIATION WITH CARBOPLA… Recruiting

2023-505078-13-00 EXTENSIVE STAGE ‐ EXTRAPULMONARY SMALL CELL CARCINOMA 4 2024-01-16
Combining anti-PD-L1 immune checkpoint inhibitor durvalumab with TLR-3 agonist rintatolimod in patients with metastatic pancreatic ductal ad… Recruiting

2024-514597-42-00 Metastatic pancreatic cancer 9 2024-01-16
A PHASE 1, OPEN-LABEL, DOSE ESCALATION AND DOSE EXPANSION STUDY OF CLN-049 FOR THE TREATMENT OF ACUTE MYELOID LEUKEMIA (AML) PATIENTS WITH M… Recruiting

2023-506572-27-00 Acute Myeloid Leukemia (AML) with Measurable Residual D 3 2024-01-12
DS-1103a Combination Therapy First-in-human (FIH) Study Recruiting

2023-503965-48-00 Advanced (unresectable or metastatic) human epidermal g 1 2024-01-11
Trial to evaluate CAR-T NKG2D CAR cell infusions in patients with advanced sarcoma Recruiting

2024-513514-35-00 Sarcoma 1 2024-01-10
A Multicenter, Open-Label, Dose-Finding Clinical Trial to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy of RV… Recruiting

2023-505911-19-00 Acute Myeloid Leukemia 4 2024-01-05
Trans-arterial treatment of patients with intra-hepatic cholangiocarcinoma not amenable to resection (TOMCAT) Recruiting

2023-504433-50-00 Intra-hepatic cholangiocarcinoma 6 2024-01-05
Primary chemoradiation versus neoadjuvant chemotherapy followed by surgery as treatment strategy for locally advanced vulvar carcinoma (VULC… Recruiting

2022-502685-25-00 The trial population will consist of patients with LAVC 10 2024-01-01
COBRA - Chemoablation for Low Grade Bladder Cancer: A single arm, prospective, open-label, investigator-initiated Phase 2 study Recruiting

2024-517106-28-00 Bladder cancer 4 2023-12-27
A study of STX-478 alone and in combination with other anticancer drugs in participants with advanced solid tumors. Recruiting

2023-504807-94-00 Breast Cancer; Advanced solid tumors including but not 7 2023-12-26
A Study Evaluating the Efficacy and Safety of Inavolisib Plus Phesgo (pertuzumab, trastuzumab, and rHuPH20 injection for SC use) versus plac… Recruiting

2022-502046-28-00 HER2-Positive, PIK3CA Mutated, Locally Advanced or Meta 5 2023-12-22
A Phase 2 Study of Teclistamab in Combination with Daratumumab or Lenalidomide in Elderly Patients with Newly Diagnosed Multiple Myeloma - I… Recruiting

2024-514101-65-00 Multiple Myeloma 4 2023-12-21
Study on the effect of 2 immunotherapy drugs in combination with radioactive glass spheres on the survival in liver cancer Recruiting

2024-515127-11-00 hepatocellular carcinoma 4 2023-12-21