Neoplasms

3,817 trials 1,526 recruiting

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A CLINICAL TRIAL TO CONFIRM THE EFFICACY OF OLAPARIB IN COMBINATION WITH BEVACIZUMAB, ADMINISTERED AS MAINTENANCE THERAPY AFTER A FRONTLINE … Ended

2022-502242-27-00 Patients with a confirmation of advanced, high grade ep 6 2023-06-16
AD ASTRA (Androgen Deprivation with Apalutamide and STereotactic RAdiotherapy) Ended

2024-517901-97-00 Localized or a locally advanced high-risk prostate canc 4 2023-06-13
A Study of EOS301984 in Adult Participants with Advanced Solid Tumors Ended

2023-503844-14-00 Advanced Solid Tumors 1 2023-06-13
Clinical study to investigate efficacy of Botensilimab (AGEN1181) as Monotherapy and in Combination with Balstilimab (AGEN2034) or Investiga… Ended

2022-502065-23-00 Refractory Metastatic Colorectal Cancer 4 2023-06-01
Radiometabolic Therapy (RMT) with 177Lu PSMA in PSMA PET/CT positive advanced/metastatic tumours: a basket trial (LUBASKET) Ended

2024-519346-75-00 PSMA PET/CT positive advanced/metastatic tumours 4 2023-05-25
Combined Pembrolizumab and Lenvatinib after definitive Chemoradiation of locally advanced HNSCC in PD-L1 positive patients (CPS≥1) Ended

2024-516536-10-00 Locally advanced head and neck squamous cell carcinoma 4 2023-05-25
A Phase 1 First-Time-in-Human, Open-Label Study of GSK4381562 Administered as Monotherapy and in Combination with Anticancer Agents in Parti… Ended

2023-509414-11-00 Neoplasms 1 2023-05-24
PHASE II STUDY FOR PATIENTS WITH ADVANCED TRIPLE NEGATIVE OR METAPLASTIC HRPOSITIVE/HER2-NEGATIVE, PIK3CA/PTEN-ALTERED BREAST CANCER TREATED… Ended

2024-512963-30-00 Locally advanced or unresectable PIK3CA and/or PTENalte 4 2023-05-24
A phase 3 clinical trial of a new combination treatment, domvanalimab and zimberelimab, plus chemotherapy, for people with an upper gastroin… Ended

2023-507522-16-00 Metastatic Esophageal or Gastric Cancer 5 2023-05-22
Study of chemotherapy and immunotherapy before and after surgery in patients with non-small cell lung cancer whose tumor is located in the u… Ended

2024-512359-19-00 Resectable Non-small cell lung cancer Pancoast tumor 4 2023-05-12
A Phase 2 clinical trial of Pembrolizumab in combination with Carboplatin and Cabazitaxel in Aggressive Variant Metastatic Castration Resist… Ended

2022-501139-17-01 Aggressive Variant Metastatic Castration Resistant Pros 4 2023-05-05
A study in metastatic breast cancer patients receiving eftilagimod alpha or placebo in combination with a standard chemotherapy (paclitaxel) Ended

2024-511023-34-00 HER2-neg/low metastatic breast cancer 10 2023-05-05
An early access study of ivosidenib in patients with a pretreated locally advanced or metastatic cholangiocarcinoma Ended

2022-501463-40-01 Locally Advanced or Metastatic Cholangiocarcinoma 5 2023-05-03
A phase II study evaluating the efficacy and safety of IMetelstat in Patients with HR myElodysplastic SyndromeS or AML failing HMA-based the… Ended

2022-500721-32-01 AML and MDS patients failing or being refractory to hyp 4 2023-05-03
A window-of-opportunity trial with high-dose vitamin C to enhance neoadjuvant immune checkpoint therapy in mismatch repair proficient colore… Ended

2022-502524-41-00 pMMR/MSS 4 2023-05-02
ETOP 22-22 ADEPPT: A study of adagrasib for patients with KRASG12C-mutant non-small cell lung cancer (NSCLC), who are elderly or who are unw… Ended

2023-510463-35-00 Patients with KRASG12C-mutant NSCLC, including patients 4 2023-04-26
IFCT-2201 ADAPTABLE A study evaluating the combination of paclitaxel-bevacizumab ± atezolizumab in patients with advanced lung cancer progre… Ended

2022-502103-30-00 advanced non-squamous non-small cell lung cancer 4 2023-04-25
A clinical trial of relacorilant (study drug) with nab-paclitaxel in patients with ovarian, fallopian tube or peritoneal cancer Ended

2024-514080-25-00 Advanced, Platinum-Resistant, High-Grade Epithelial Ova 5 2023-04-21
LOGGIC/FIREFLY-2: DAY101 vs. Standard of Care Chemotherapy in Pediatric Patients with Low-Grade Glioma Requiring First-Line Systemic Therapy Ended

2024-510742-13-00 Pediatric low-grade glioma harboring an activating RAF 5 2023-04-19
Phase 2 study of belantamab mafodotin in combination with bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma Ended

2024-516250-22-00 The study will enroll adult participants with RRMM who 4 2023-04-17
ETOP 18-21 AMAZE-lung: A clinical study exploring the effect of amivantamab and lazertinib plus bevacizumab treatment, in people diagnosed w… Ended

2024-512288-29-00 Patients with EGFR-mutant (L858R or del19 only) advance 4 2023-04-11
Clinical Study of Subcutaneous Pembrolizumab Coformulated with Hyaluronidase (MK-3475A) versus Intravenous Pembrolizumab, Given with Chemoth… Ended

2022-501506-36-00 First-line treatment of participants with metastatic no 5 2023-04-11
International treatment-extension study in adult participants with multiple myeloma and who have derived clinical benefit from isatuximab Ended

2023-507180-19-00 Cancer 4 2023-04-05
A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Patients with Previously Untreated Locally Advanced Unresectable or Met… Ended

2023-505816-39-00 Untreated Locally Advanced Unresectable or Metastatic R 4 2023-04-04