Nervous System Diseases

1,005 trials 421 recruiting

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Efficacy and Safety Study of Nipocalimab for Adults with Active Inflammatory Myopathies Ended

2023-505314-20-00 Active Idiopathic Inflammatory Myopathies (IIM) 4 2023-01-20
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Early… Ended

2024-515198-91-00 Dominantly Inherited Alzheimer Disease (DIAD) 10 2022-12-20
A trial to determine the safety and tolerability of transplanted stem cellderived dopamine neurons to the brains of individuals with Parkins… Ended

2024-511237-35-00 Parkinson's disease 7 2022-11-30
AMANTADINE AND TRANSCRANIAL MAGNETIC TRANSCRANIAL MAGNETIC STIMULATION FOR FATIGUE IN MULTIPLE SCLEROSIS: A PHASE III, CONTROLLED, RANDOMISE… Ended

2024-516732-97-00 multiple sclerosis (MS) 5 2022-11-28
Safety and Efficacy of ALXN1720 in Adults with Generalized Myasthenia Gravis. Ended

2023-508284-77-00 Generalized Myasthenia Gravis with autoantibodies again 5 2022-11-16
A study into the efficacy and safety of dazucorilant (CORT113176) in patients with Amyotrophic Lateral Sclerosis Ended

2024-514082-19-00 Amyotrophic Lateral Sclerosis 4 2022-11-04
A study to learn if Rozanolixizumab works and is safe over a long period in adults with relapsing myelin oligodendrocyte glycoprotein antibo… Ended

2023-509237-39-00 Myelin oligodendrocyte glycoprotein antibody-associated 5 2022-08-02
A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients with Multiple Sclerosis Ended

2023-505974-14-00 Multiple Sclerosis (MS) 5 2022-06-23
Efficacy and safety of remibrutinib compared to teriflunomide in participants with relapsing multiple sclerosis, followed by long term treat… Ended

2023-509345-12-00 Multiple Sclerosis 5 2022-06-22
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Patients with Myelin Oligodendrocyte Gly… Ended

2023-507196-22-00 Myelin Oligodendrocyte Glycoprotein Antibody-Associated 5 2022-06-20
A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Participants With Spinal Muscular A… Ended

2023-506761-65-00 Spinal Muscular Atrophy (SMA) 10 2022-04-08
NOR-CACTUS Ended

2024-511223-34-00 Carpal Tunnel Syndrome 6 2022-04-08
An international randomized clinical study, measuring safety and effectiveness of basimglurant for the treatment of pain in patients with Tr… Ended

2024-514497-41-00 Trigeminal neuralgia 10 2022-03-24
A Multi-Center, Randomized, Double-Blinded Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 versus Placebo in Adu… Ended

2024-514619-88-00 Relapsing Multiple Sclerosis 5 2022-03-18
Personalized dosing of ocrelizumab in MS Ended

2024-513193-22-00 Multiple Sclerosis 11 2022-03-16
A Multi-Center, Randomized, Double-Blinded Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 versus Placebo in Adu… Ended

2024-514618-11-00 Relapsing Multiple Sclerosis 5 2022-03-01
Single-cell deep phenotyping of B lymphocytes to personalize immunotherapy in patients with Myasthenia Gravis: clinical trial to evaluate th… Ended

2024-518939-12-00 Generalized Myasthenia Gravis 5 2022-02-28
Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children aged ≥ 1 to < 7 Years with Neurofibromatosis Type 1… Ended

2023-506357-38-00 Neurofibromatosis Type 1 (NF1) Related Plexiform Neurof 9 2022-02-17
A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison with Fingolimod in Children and Adolescents with Relapsing-Remitting Mu… Ended

2023-506516-40-00 Relapsing-Remitting Multiple Sclerosis 5 2022-02-11
Efficacy and safety of remibrutinib compared to teriflunomide in participants with relapsing multiple sclerosis, followed by long term treat… Ended

2023-509372-41-00 Multiple Sclerosis 5 2022-01-30
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ION363 in Amyotrophic Lateral Sclerosis Participants With… Ended

2024-512163-31-00 Amyotrophic Lateral Sclerosis with Fused in Sarcoma mut 10 2022-01-26
A Study to Investigate the Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis Ended

2022-502619-13-00 Relapsing Multiple Sclerosis 4 2022-01-25
Efficacy and Safety of Selumetinib in Adults with NF1 who have Symptomatic, Inoperable Plexiform Neurofibromas. Ended

2023-507336-20-00 Neurofibromatosis Type 1 (NF1) with Symptomatic, Inoper 5 2021-12-08
Safety and Efficacy of AMT-130 in European Adults with Early Manifest Huntington Disease Ended

2024-511766-37-00 Huntington’s Disease 7 2021-10-07