A phase I trial to assess safety and immunogenicity of an HLAII-targeted DNA vaccine against influenza H7N9

2022-500706-18-01 Human pharmacology (Phase I) - First administration to humans Ongoing, recruitment ended

Start 11 Sep 2023 · Status Ongoing, recruitment ended · 1 EU/EEA countries · 1 sites

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - First administration to humans
Status Ongoing, recruitment ended
Participants planned 30
Countries 1
Sites 1

Influenza prophylaxis

Key facts

Sponsor
Oslo University Hospital Hf
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Virus Diseases [C02]
Trial duration
11 Sep 2023 → ongoing
Decision date (initial)
2023-06-26
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Influenza prophylaxis

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Oslo University Hospital Hf

Sponsor organisation
Oslo University Hospital Hf
Address
Taarnbygget, Kirkeveien 166 Kirkeveien 166
City
Oslo
Postcode
0450
Country
Norway

Scientific contact point

Organisation
Oslo University Hospital Hf
Contact name
Gunnveig Grødeland

Public contact point

Organisation
Oslo University Hospital Hf
Contact name
Gunnveig Grødeland

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Norway Ongoing, recruitment ended 30 1
Rest of world 0

Investigational sites

Norway

1 site · Ongoing, recruitment ended
Oslo University Hospital Hf
Infectious Diseases, Taarnbygget, Kirkeveien 166, Oslo

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Norway 2023-09-11 2023-09-11 2025-10-17

Application history

7 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-02-28 Norway Acceptable
2023-06-19
2023-06-26
2 SUBSTANTIAL MODIFICATION SM-1 2023-07-04 Norway Acceptable
2023-07-19
2023-07-19
3 SUBSTANTIAL MODIFICATION SM-2 2023-08-24 Norway Acceptable 2023-09-04
4 NON SUBSTANTIAL MODIFICATION NSM-1 2023-09-13 Norway Acceptable
2023-06-19
2023-09-13
5 SUBSTANTIAL MODIFICATION SM-4 2023-10-17 Norway Acceptable
2023-11-30
2023-11-30
6 NON SUBSTANTIAL MODIFICATION NSM-2 2023-11-30 Norway 2023-11-30
7 SUBSTANTIAL MODIFICATION SM-5 2024-08-06 Norway Acceptable
2024-09-30
2024-09-30