RElapse in previously irradiated Prostate bed : a phase I/II study of stereotactic Ablative reIRradiation potentiated by Metformine (REPAIR GETUG P16)

2022-502642-27-00 Protocol ICO-2020-01 REPAIR Phase I and Phase II (Integrated) - Other Ongoing, recruiting

Start 26 Nov 2020 · Status Ongoing, recruiting · 1 EU/EEA countries · 11 sites · Protocol ICO-2020-01 REPAIR

Overview

Sponsor-declared trial summary

Phase Phase I and Phase II (Integrated) - Other
Status Ongoing, recruiting
Participants planned 44
Countries 1
Sites 11

RElapse in previously irradiated Prostate bed

Key facts

Sponsor
Institut De Cancerologie De L Ouest
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male
Therapeutic area
Diseases [C] - Neoplasms [C04]
Trial duration
26 Nov 2020 → ongoing
Decision date (initial)
2024-04-09
Transition trial
Yes
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2022-502642-27-00
EudraCT number
2020-001685-11
ClinicalTrials.gov
NCT04536805

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

RElapse in previously irradiated Prostate bed

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Institut De Cancerologie De L Ouest

Sponsor organisation
Institut De Cancerologie De L Ouest
Address
Boulevard Jacques Monod
City
Saint Herblain
Postcode
44805
Country
France

Scientific contact point

Organisation
Institut De Cancerologie De L Ouest
Contact name
Stéphane SUPIOT

Public contact point

Organisation
Institut De Cancerologie De L Ouest
Contact name
Lucie LABARRE

Locations

1 EU/EEA country · 11 investigational sites

By country

CountryMS statusPlanned subjectsSites
France Ongoing, recruiting 44 11
Rest of world 0

Investigational sites

France

11 sites · Ongoing, recruiting
Institut De Cancerologie De L Ouest
Radiotherapy, Bd Du Professeur Jacques Monod, 44800, St Herblain
Clinique Victor Hugo
Radiotherapy, 18 Rue Victor Hugo, Cs 81514, Le Mans Cedex 2
Centre Hospitalier Regional Et Universitaire De Brest
Radiotherapy, 2 Avenue Marechal Foch, 29200, Brest
Centre Leon Berard
Radiotherapy, 28 Rue Laennec, 69008, Lyon
Centre Hospitalier Regional Universitaire De Tours
Radiotherapy, 2 Boulevard Tonnelle, 37000, Tours
Institut De Cancerologie De L Ouest
Radiotherapy, 15 Rue Andre Boquel, 49100, Angers
Centr Georges Francois Leclerc
Radiotherapy, 1 Rue Professeur Marion, 21000, Dijon
Centre Oscar Lambret
Radiotherapy, 3 Rue Frederic Combemale, 59000, Lille
Pole Sante Leonard De Vinci
Radiotherapy, 1 Avenue Du Professeur Alexandre Minkowski, 37170, Chambray Les Tours
Centre Henri Becquerel
Radiotherapy, 1 Rue D Amiens, 76000, Rouen
Centre Regional Lutte Contre Le Cancer
Radiotherapy, Batiment Icans, 17 Rue Albert Calmette, Strasbourg

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
France 2020-11-26 2020-11-26

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-01-23 France Acceptable
2024-04-05
2024-04-09
2 SUBSTANTIAL MODIFICATION SM-1 2025-10-13 France Acceptable
2025-10-24
2025-10-27