A clinical study investigating OM-85-IN safety and tolerability in healthy volunteers and mild allergic asthma patients

2022-503053-19-00 Protocol BV-2022/11 Human pharmacology (Phase I) - First administration to humans Ended

Start 14 Jun 2024 · End 20 Feb 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol BV-2022/11

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - First administration to humans
Status Ended
Participants planned 41
Countries 1
Sites 1

Mild allergic asthma

Key facts

Sponsor
OM Pharma S.A.
Participant type
Healthy volunteers, Patients
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Respiratory Tract Diseases [C08]
Trial duration
14 Jun 2024 → 20 Feb 2025
Decision date (initial)
2023-10-17
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Mild allergic asthma

VersionLevelCodeTermSystem organ class
21.1 LLT 10001705 Allergic asthma 10038738

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

OM Pharma S.A.

Sponsor organisation
OM Pharma S.A.
Address
Rue Du Bois-Du-Lan 22
City
Meyrin
Postcode
1217
Country
Switzerland

Scientific contact point

Organisation
OM Pharma S.A.
Contact name
Clinical Development Department

Public contact point

Organisation
OM Pharma S.A.
Contact name
Clinical Development Department

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Ended 41 1
Rest of world 0

Investigational sites

Germany

1 site · Ended
The Fraunhofer Institute For Toxicology And Experimental Medicine ITEM
#001:Toxicology and Experimental Medicine Clinical Airway Research, Nikolai-Fuchs-Strasse 1, Gross Buchholz, Hanover

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Germany 2024-06-14 2025-02-19 2024-06-28 2025-01-22

Application history

3 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-06-27 Germany Acceptable
2023-10-16
2023-10-17
2 SUBSTANTIAL MODIFICATION SM-1 2024-03-26 Germany Acceptable
2024-04-26
2024-06-14
3 NON SUBSTANTIAL MODIFICATION NSM-1 2024-10-17 Germany Acceptable
2024-04-26
2024-10-17