Investigation of safety, tolerability and pharmacokinetics of multiple doses of NNC0113‑6856 in healthy participants, including a subset of healthy Japanese participants

2023-503891-26-00 Protocol NN9904-5008 Human pharmacology (Phase I) - Other Ended

Start 29 Sep 2023 · End 23 Apr 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol NN9904-5008

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 170
Countries 1
Sites 1

Type 2 diabetes

Key facts

Sponsor
Novo Nordisk A/S
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Nutritional and Metabolic Diseases [C18]
Trial duration
29 Sep 2023 → 23 Apr 2025
Decision date (initial)
2023-08-25
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2023-503891-26-00
WHO UTN
U1111-1284-5743

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Type 2 diabetes

VersionLevelCodeTermSystem organ class
21.1 LLT 10045242 Type II diabetes mellitus 10027433

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Novo Nordisk A/S

Sponsor organisation
Novo Nordisk A/S
Address
Novo Alle 1
City
Bagsvaerd
Postcode
2880
Country
Denmark

Scientific contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission Hub

Public contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission Hub

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Ended 170 1
Rest of world 0

Investigational sites

Germany

1 site · Ended
PROFIL Institut fuer Stoffwechselforschung GmbH
N/A, Hellersbergstrasse 9, Hammfeld, Neuss

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Germany 2023-09-29 2025-04-23 2023-10-02 2025-01-16

Application history

6 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-06-13 Germany Acceptable
2023-08-24
2023-08-25
2 SUBSTANTIAL MODIFICATION SM-1 2024-01-12 Germany Acceptable
2024-02-05
2024-02-09
3 SUBSTANTIAL MODIFICATION SM-2 2024-04-16 Germany Acceptable
2024-05-03
2024-05-06
4 SUBSTANTIAL MODIFICATION SM-3 2024-07-01 Germany Acceptable
2024-07-25
2024-07-26
5 SUBSTANTIAL MODIFICATION SM-4 2024-12-04 Germany Not acceptable
2025-01-27
2025-02-03
6 SUBSTANTIAL MODIFICATION SM-5 2025-03-25 Germany Acceptable
2025-04-24
2025-04-25