A research study comparing the effect of different dosing conditions on blood levels of semaglutide in a new tablet composition in healthy participants

2023-503949-65-00 Protocol NN9924-4977 Human pharmacology (Phase I) - Other Ended

Start 7 Aug 2023 · End 18 Apr 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol NN9924-4977

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 120
Countries 1
Sites 1

Type 2 Diabetes

Key facts

Sponsor
Novo Nordisk A/S
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male
Therapeutic area
Diseases [C] - Nutritional and Metabolic Diseases [C18]
Trial duration
7 Aug 2023 → 18 Apr 2024
Decision date (initial)
2023-07-21
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2023-503949-65-00
WHO UTN
U1111-1281-4819

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Type 2 Diabetes

VersionLevelCodeTermSystem organ class
21.1 LLT 10045242 Type II diabetes mellitus 10027433

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Novo Nordisk A/S

Sponsor organisation
Novo Nordisk A/S
Address
Novo Alle 1
City
Bagsvaerd
Postcode
2880
Country
Denmark

Scientific contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission Hub

Public contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission Hub

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Ended 120 1
Rest of world 0

Investigational sites

Germany

1 site · Ended
PROFIL Institut fuer Stoffwechselforschung GmbH
N/A, Hellersbergstrasse 9, Hammfeld, Neuss

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Germany 2023-08-07 2024-04-18 2023-08-12 2024-03-01

Application history

3 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-05-29 Germany Acceptable
2023-07-11
2023-07-21
2 SUBSTANTIAL MODIFICATION SM-1 2023-09-18 Germany Acceptable
2023-10-11
2023-10-12
3 SUBSTANTIAL MODIFICATION SM-2 2023-11-17 Germany Acceptable
2023-12-11
2023-12-12