A study of how CagriSema works on appetite in people with excess body weight

2023-504782-23-00 Protocol NN9838-4944 Human pharmacology (Phase I) - Other Ended

Start 9 Feb 2024 · End 8 Dec 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol NN9838-4944

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 150
Countries 1
Sites 1

Obesity

Key facts

Sponsor
Novo Nordisk A/S
Participant type
Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Nutritional and Metabolic Diseases [C18]
Trial duration
9 Feb 2024 → 8 Dec 2025
Decision date (initial)
2023-12-12
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2023-504782-23-00
WHO UTN
U1111-1286-0512

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Obesity

VersionLevelCodeTermSystem organ class
20.0 PT 10029883 Obesity 100000004861

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Novo Nordisk A/S

Sponsor organisation
Novo Nordisk A/S
Address
Novo Alle 1
City
Bagsvaerd
Postcode
2880
Country
Denmark

Scientific contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission Hub

Public contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission Hub

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Ended 150 1
Rest of world 0

Investigational sites

Germany

1 site · Ended
Charite Research Organisation GmbH
N/A, Chariteplatz 1, Mitte, Berlin

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Germany 2024-02-09 2025-12-08 2024-02-15 2024-10-17

Application history

7 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-09-25 Germany Acceptable
2023-12-08
2023-12-12
2 NON SUBSTANTIAL MODIFICATION NSM-1 2024-01-10 Germany Acceptable
2023-12-08
2024-01-10
3 SUBSTANTIAL MODIFICATION SM-1 2024-05-20
4 SUBSTANTIAL MODIFICATION SM-2 2024-07-09 Germany Acceptable
2024-07-26
2024-08-05
5 SUBSTANTIAL MODIFICATION SM-3 2024-08-23 Germany Acceptable
2024-09-16
2024-09-17
6 SUBSTANTIAL MODIFICATION SM-4 2025-01-31 Germany Acceptable
2025-02-20
2025-02-26
7 SUBSTANTIAL MODIFICATION SM-5 2025-08-21 Germany Acceptable
2025-09-30
2025-09-30