A study to test how a new long-acting insulin works in the body of patients with type 2 diabetes during exercise and prolonged fasting.

2023-505012-38-00 Protocol NN1436-7615 Human pharmacology (Phase I) - Other Ended

Start 21 Feb 2024 · End 14 Apr 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol NN1436-7615

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 30
Countries 1
Sites 1

Type 2 diabetes

Key facts

Sponsor
Novo Nordisk A/S
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Nutritional and Metabolic Diseases [C18]
Trial duration
21 Feb 2024 → 14 Apr 2025
Decision date (initial)
2024-02-12
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

External identifiers

EU CT number
2023-505012-38-00
WHO UTN
U1111-1285-1665

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Type 2 diabetes

VersionLevelCodeTermSystem organ class
21.1 LLT 10045242 Type II diabetes mellitus 10027433

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Novo Nordisk A/S

Sponsor organisation
Novo Nordisk A/S
Address
Novo Alle 1
City
Bagsvaerd
Postcode
2880
Country
Denmark

Scientific contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission Hub

Public contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission Hub

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Austria Ended 30 1
Rest of world 0

Investigational sites

Austria

1 site · Ended
Medical University Of Graz
NA, Neue Stiftingtalstrasse 6, 8010, Graz

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Austria 2024-02-21 2025-04-14 2024-02-26 2024-12-19

Application history

6 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-10-04 Austria Acceptable
2024-02-05
2024-02-12
2 SUBSTANTIAL MODIFICATION SM-1 2024-03-13 Austria Acceptable
2024-04-29
2024-05-06
3 SUBSTANTIAL MODIFICATION SM-2 2024-06-11 Austria Acceptable
2024-07-29
2024-08-05
4 NON SUBSTANTIAL MODIFICATION NSM-1 2024-08-12 Austria Acceptable
2024-07-29
2024-08-12
5 SUBSTANTIAL MODIFICATION SM-3 2024-09-17 Austria Acceptable 2024-11-04
6 SUBSTANTIAL MODIFICATION SM-4 2024-12-17 Austria Acceptable
2025-02-17
2025-02-23