Bioequivalence study between two fluticasone propionate 250μg/salmeterol 50μg inhalation powders

2023-505198-34-00 Protocol BECRO/RESP/AEROPK250 Human pharmacology (Phase I) - Bioequivalence study Ended

Start 31 Jul 2023 · End 22 Mar 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol BECRO/RESP/AEROPK250

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Bioequivalence study
Status Ended
Participants planned 34
Countries 1
Sites 1

Healthy volunteers.Regular treatment of bronchial asthma, where a combination product containing a corticosteroid and a long-acting beta2-adrenergic agonist (LABA) is indicated for: •Twice-daily treatment of asthma in patients aged 4 years and older. •Maintenance treatment of airflow obstruction and reducing exacerbations in patients with chronic obstructive pulmonary disease (COPD).

Key facts

Sponsor
Respirent Pharmaceuticals Co. Ltd.
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Respiratory Tract Diseases [C08]
Trial duration
31 Jul 2023 → 22 Mar 2024
Decision date (initial)
2023-07-26
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Healthy volunteers.Regular treatment of bronchial asthma, where a combination product containing a corticosteroid and a long-acting beta2-adrenergic agonist (LABA) is indicated for: •Twice-daily treatment of asthma in patients aged 4 years and older. •Maintenance treatment of airflow obstruction and reducing exacerbations in patients with chronic obstructive pulmonary disease (COPD).

VersionLevelCodeTermSystem organ class
20.0 PT 10003553 Asthma 100000004855
21.1 PT 10009033 Chronic obstructive pulmonary disease 100000004855

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Respirent Pharmaceuticals Co. Ltd.

Sponsor organisation
Respirent Pharmaceuticals Co. Ltd.
Address
High-Tech Industrial Park, 5 -190 Yunhan Drive, Shuitu 5 -190 Yunhan Drive Shuitu
City
Chongqing
Postcode
400714
Country
China

Scientific contact point

Organisation
Respirent Pharmaceuticals Co. Ltd.
Contact name
Clinical Trial Information

Public contact point

Organisation
Respirent Pharmaceuticals Co. Ltd.
Contact name
Clinical Trial Information

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Greece Ended 34 1
Rest of world 0

Investigational sites

Greece

1 site · Ended
BECRO Ltd Clinical Facility General clinic 'Eftychios Patsidis'
BECRO Ltd Clinical facility General clinic 'Eftychios Patsidis', 75, Theofrastou str., Larissa

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Greece 2023-07-31 2024-03-22 2023-08-01 2023-08-18

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-05-23 Greece Acceptable with conditions
2023-07-25
2023-07-26