PET study of changes in [11C]AZ14132516 uptake following administration of AZD7798 to healthy participants and patients with Crohn’s disease

2023-505471-78-00 Protocol D9690C00004 Human pharmacology (Phase I) - Other Ended

Start 25 Sep 2023 · End 8 Oct 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol D9690C00004

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 14
Countries 1
Sites 1

Crohn's Disease

Key facts

Sponsor
Astrazeneca AB
Participant type
Patients, Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Digestive System Diseases [C06]
Trial duration
25 Sep 2023 → 8 Oct 2024
Decision date (initial)
2023-08-31
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Crohn's Disease

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Astrazeneca AB

Sponsor organisation
Astrazeneca AB
Address
Astraallen Gartuna, Karlebyhus Byggnad 674 Karlebyhus Byggnad 674
City
Sodertalje
Postcode
151 85
Country
Sweden

Scientific contact point

Organisation
Astrazeneca AB
Contact name
AstraZeneca Clinical Study Information Center

Public contact point

Organisation
Astrazeneca AB
Contact name
AstraZeneca Clinical Study Information Center

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Sweden Ended 14 1
Rest of world 0

Investigational sites

Sweden

1 site · Ended
Karolinska University Hospital
Fas-1 enheten, M62, Halsovagen, Flemingsberg, Huddinge

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Sweden 2023-09-25 2024-10-08 2023-09-25 2024-08-21

Application history

3 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-06-14 Sweden Acceptable
2023-08-30
2023-08-31
2 SUBSTANTIAL MODIFICATION SM-1 2024-02-26 Sweden Acceptable
2024-04-03
2024-04-09
3 NON SUBSTANTIAL MODIFICATION NSM-2 2024-05-22 Sweden Acceptable
2024-04-03
2024-05-22