A monocentric Phase I pivotal pharmacology study for the determination of the local and systemic exposure of locally applied Minocycline in periodontal pockets via a newly developed pharmaceutical formulation for the treatment of patients with recurrent or persistent periodontitis

2023-506126-36-00 Protocol MinoPro-101 Human pharmacology (Phase I) - Other Authorised, recruitment pending

Status Authorised, recruitment pending · 1 EU/EEA countries · 1 sites · Protocol MinoPro-101

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Authorised, recruitment pending
Participants planned 24
Countries 1
Sites 1

Periodontitis

Key facts

Sponsor
PerioTrap Pharmaceuticals GmbH
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Stomatognathic Diseases [C07], Phenomena and Processes [G] - Microbiological Phenomena [G06], Diseases [C] - Bacterial Infections and Mycoses [C01]
Decision date (initial)
2023-10-16
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Periodontitis

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

PerioTrap Pharmaceuticals GmbH

Sponsor organisation
PerioTrap Pharmaceuticals GmbH
Address
Weinbergweg 22, Kroellwitz Kroellwitz
City
Halle (saale)
Postcode
06120
Country
Germany

Scientific contact point

Organisation
PerioTrap Pharmaceuticals GmbH
Contact name
Mirko Buchholz

Public contact point

Organisation
PerioTrap Pharmaceuticals GmbH
Contact name
Pierre Tangermann

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Authorised, recruitment pending 24 1
Rest of world 0

Investigational sites

Germany

1 site · Authorised, recruitment pending
BAG Dr. T. Schütz / ZA J. Schmidtke
Zahnerhaltung und Parodontologie, Altenburger Strasse 13, 04552, Borna

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-07-14 Germany Acceptable
2023-09-08
2023-10-16
2 SUBSTANTIAL MODIFICATION SM-1 2023-10-18 Germany Acceptable 2023-10-31