Dose-finding and safety study of a new Shigella vaccine combined with an adjuvant in the Netherlands and Zambia

2023-506394-35-02 Protocol SUNSHINE Human pharmacology (Phase I) - Other Ended

Start 12 Sep 2024 · End 18 Feb 2026 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol SUNSHINE

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 85
Countries 1
Sites 1

Vaccination against shigellosis (in healthy adults)

Key facts

Sponsor
Academisch Ziekenhuis Leiden
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Digestive System Diseases [C06], Diseases [C] - Bacterial Infections and Mycoses [C01]
Trial duration
12 Sep 2024 → 18 Feb 2026
Decision date (initial)
2024-07-02
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2023-506394-35-02
ClinicalTrials.gov
NCT05961059

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Vaccination against shigellosis (in healthy adults)

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Academisch Ziekenhuis Leiden

Sponsor organisation
Academisch Ziekenhuis Leiden
Address
Albinusdreef 2
City
Leiden
Postcode
2333 ZA
Country
Netherlands

Scientific contact point

Organisation
Academisch Ziekenhuis Leiden
Contact name
Meta Roestenberg

Public contact point

Organisation
Academisch Ziekenhuis Leiden
Contact name
Meta Roestenberg

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Netherlands Ended 50 1
Rest of world
Zambia
35

Investigational sites

Netherlands

1 site · Ended
Academisch Ziekenhuis Leiden
Parasitology and Infectious Diseases, Albinusdreef 2, 2333 ZA, Leiden

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Netherlands 2024-09-12 2025-09-26 2024-09-12 2025-02-05

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-04-05 Netherlands Acceptable
2024-07-02
2024-07-02