Randomised, relative bioavailability clinical trial of amylmetacresol, dichlorobenzyl alcohol, lidocaine and vitamin c lozenges after a single oral dose administration to healthy volunteers under fasting conditions in a crossover design.

2023-507599-34-00 Protocol G23-00 Human pharmacology (Phase I) - Bioequivalence study Ended

Start 11 Mar 2024 · End 15 Apr 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol G23-00

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Bioequivalence study
Status Ended
Participants planned 60
Countries 1
Sites 1

healthy volunteer

Key facts

Sponsor
Geiser Pharma S.L.
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Respiratory Tract Diseases [C08]
Trial duration
11 Mar 2024 → 15 Apr 2024
Decision date (initial)
2023-12-04
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

healthy volunteer

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Geiser Pharma S.L.

Sponsor organisation
Geiser Pharma S.L.
Address
Labiano Bidea 45b, Mutilva Mutilva
City
Aranguren
Postcode
31192
Country
Spain

Scientific contact point

Organisation
Geiser Pharma S.L.
Contact name
Francisco Abad Santos

Public contact point

Organisation
Geiser Pharma S.L.
Contact name
Ainara Lecumberri

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Spain Ended 60 1
Rest of world 0

Investigational sites

Spain

1 site · Ended
Hospital Universitario De La Princesa
Clinical pharmacology, Calle De Diego De Leon 62, 28006, Madrid

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Spain 2024-03-11 2024-04-15 2024-03-12 2024-04-05

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-09-08 Spain Acceptable with conditions
2023-12-04
2023-12-04
2 SUBSTANTIAL MODIFICATION SM-1 2024-02-05 Spain Acceptable
2024-03-01
2024-03-01