An exploratory study to investigate the effect of FE 999302 when given together with follitropin delta during controlled ovarian stimulation

2023-507630-25-00 Protocol 000426 Human pharmacology (Phase I) - Other Ended

Start 14 Jun 2024 · End 5 Sep 2025 · Status Ended · 5 EU/EEA countries · 15 sites · Protocol 000426

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 600
Countries 5
Sites 15

Infertility in women undergoing assisted reproductive technologies (ART)

Key facts

Sponsor
Ferring Pharmaceuticals A/S
Participant type
Patients
Age range
18-64 years
Gender
Female
Therapeutic area
Diseases [C] - Female Urogenital Diseases and Pregnancy Complications [C13]
Trial duration
14 Jun 2024 → 5 Sep 2025
Decision date (initial)
2024-05-23
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2023-507630-25-00
WHO UTN
U1111-1293-5452

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Infertility in women undergoing assisted reproductive technologies (ART)

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Ferring Pharmaceuticals A/S

Sponsor organisation
Ferring Pharmaceuticals A/S
Address
Amager Strandvej 405
City
Kastrup
Postcode
2770
Country
Denmark

Scientific contact point

Organisation
Ferring Pharmaceuticals A/S
Contact name
Sarah Grover

Public contact point

Organisation
Ferring Pharmaceuticals A/S
Contact name
Clinical and Translational Sciences

Locations

5 EU/EEA countries · 15 investigational sites

By country

CountryMS statusPlanned subjectsSites
Belgium Ended 100 2
Czechia Ended 100 3
Denmark Ended 100 2
Norway Ended 100 3
Spain Ended 200 5
Rest of world 0

Investigational sites

Belgium

2 sites · Ended
UZ Brussel
Center of Reproductive Medicine, Laarbeeklaan 101, 1090, Jette
Antwerp University Hospital
Center of Reproductive Medicine, Drie Eikenstraat 655, 2650, Edegem

Czechia

3 sites · Ended
Ivf Cube SE
Clinic for Assisted Reproduction, Evropska 423/178, 160 00, Prague
FertiCare SE
-, Radlicka 3185/1c, Smichov, Prague
Gynem s.r.o.
Gynem Fertility Clinic, Na Orechovce 576/7, Stresovice, Prague

Denmark

2 sites · Ended
Rigshospitalet
Fertility Department, Blegdamsvej 9, 2100, Copenhagen Oe
Hvidovre Hospital
Obstetrics and Gynecology, The Fertility Clinic, Kettegaard Alle 30, 2650, Hvidovre

Norway

3 sites · Ended
Sykehuset Telemark HF
Fertilitetsavdelingen, Ulefossvegen 55, 3710, Skien
Medicus Trondheim AS
Gynaecology, Reproductive Medicine, Beddingen 8, 7042, Trondheim
Medicus Bergen AS
-, Bredalsmarken 15, 5006, Bergen

Spain

5 sites · Ended
Ginefiv S.L.
Obstetrics and gynaecology, Calle De Zurbano 51, 28010, Madrid
Ivi Sevilla S.L.
Reproductive Medicine, Calle Americo Vespucio 19, Parque Cientifico Y Tecnologico Cartuja 93, Sevilla
Ivi Madrid S.L.
Reproductive Medicine, Avenida Talgo 68-70, 28023, Madrid
Ivi Valencia S.L.
Reproductive Medicine, Placa Policia Local 3, 46015, Valencia
Hospital Universitari Dexeus Grupo Quironsalud
Department of Gynecology and Obstetrics, Calle De Sabino Arana 5-19, 08028, Barcelona

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Belgium 2024-06-24 2024-09-10
Czechia 2024-06-14 2024-06-21
Denmark 2024-08-02 2024-08-14
Norway 2024-11-07 2024-11-13
Spain 2024-06-24 2024-07-05

Application history

6 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-02-02 Denmark Acceptable
2024-05-21
2024-05-22
2 SUBSTANTIAL MODIFICATION SM-1 2024-07-05 Denmark Acceptable
2024-08-27
2024-08-27
3 NON SUBSTANTIAL MODIFICATION NSM-2 2024-09-30 Acceptable
2024-08-27
2024-09-30
4 NON SUBSTANTIAL MODIFICATION NSM-4 2024-11-07 Denmark Acceptable
2024-08-27
2024-11-07
5 SUBSTANTIAL MODIFICATION SM-2 2025-01-29 Denmark Acceptable
2025-04-25
2025-04-25
6 NON SUBSTANTIAL MODIFICATION NSM-6 2025-07-04 Acceptable
2025-04-25
2025-07-04