A phase 1, open-label, cross-over study in healthy volunteers to assess the pharmacokinetic profile of Prazosin and Cyproheptadine following single dose oral administration of KT110 tablet and following administration of Alpress and Periactine marketed tablets

2023-507788-20-00 Protocol OP111821.KIN Human pharmacology (Phase I) - First administration to humans Ended

Start 11 Apr 2024 · End 29 Jul 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol OP111821.KIN

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - First administration to humans
Status Ended
Participants planned 8
Countries 1
Sites 1

alcohol use disorder

Key facts

Sponsor
Kinnov Therapeutics
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Nervous System Diseases [C10]
Trial duration
11 Apr 2024 → 29 Jul 2024
Decision date (initial)
2024-03-22
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

alcohol use disorder

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Kinnov Therapeutics

Sponsor organisation
Kinnov Therapeutics
Address
3, allée du titane
City
Orléans
Postcode
45100
Country
France

Scientific contact point

Organisation
Kinnov Therapeutics
Contact name
Lucas BIELA

Public contact point

Organisation
Kinnov Therapeutics
Contact name
Lucas BIELA

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
France Ended 8 1
Rest of world 0

Investigational sites

France

1 site · Ended
Eurofins Optimed
Not applicable, 1 Rue Des Essarts, 38610, Gieres

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
France 2024-04-11 2024-07-29 2024-04-11 2024-07-25

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-11-16 France Acceptable
2024-03-18
2024-03-22
2 SUBSTANTIAL MODIFICATION SM-1 2024-03-23 France Acceptable 2024-03-26