A Study to Learn If the Study Medicine Called Vepdegestrant Changes How the Body Processes the Other Study Medicine Called Midazolam

2023-508518-40-00 Human pharmacology (Phase I) - Other Ended

Start 5 Feb 2024 · End 14 May 2024 · Status Ended · 1 EU/EEA countries · 1 sites

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 16
Countries 1
Sites 1

ER+/HER2 positive breast cancer

Key facts

Sponsor
Pfizer Inc.
Participant type
Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Female
Therapeutic area
Diseases [C] - Neoplasms [C04]
Trial duration
5 Feb 2024 → 14 May 2024
Decision date (initial)
2024-01-31
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

ER+/HER2 positive breast cancer

VersionLevelCodeTermSystem organ class
23.0 LLT 10070575 Estrogen receptor positive breast cancer 10029104

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Pfizer Inc.

Sponsor organisation
Pfizer Inc.
Address
66 Hudson Boulevard East
City
New York
Postcode
10001-2189
Country
United States

Scientific contact point

Organisation
Pfizer Inc.
Contact name
Clinical Medical Lead

Public contact point

Organisation
Pfizer Inc.
Contact name
Clinical Medical Lead

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Belgium Ended 16 1
Rest of world 0

Investigational sites

Belgium

1 site · Ended
Pfizer Clinical Research Unit
N/A, Route de Lennik 808, B-1070, Brussels

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Belgium 2024-02-05 2024-05-13 2024-02-08 2024-03-26

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-12-07 Belgium Acceptable
2024-01-30
2024-01-31