[HIBOU] : A phase I, single-center, randomized, double-blind, single-dose escalation, placebo-controlled clinical study to evaluate the safety, tolerability and pharmacokinetics of IMP21052 administered intravenously in three groups of healthy male and female volunteers

2023-509035-30-00 Protocol HIBOU-2023PBMD07 Human pharmacology (Phase I) - First administration to humans Ended

Start 18 Jan 2024 · End 16 Dec 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol HIBOU-2023PBMD07

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - First administration to humans
Status Ended
Participants planned 40
Countries 1
Sites 1

Antidote

Key facts

Sponsor
Direction Centrale Du Service De Sante Des Armees
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Pathological Conditions, Signs and Symptoms [C23], Phenomena and Processes [G] - Musculoskeletal and Neural Physiological Phenomena [G11], Diseases [C] - Disorders of Environmental Origin [C21]
Trial duration
18 Jan 2024 → 16 Dec 2024
Decision date (initial)
2024-01-02
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Antidote

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Direction Centrale Du Service De Sante Des Armees

2 Total trials 2 Ended
Academic / Non-commercial
Sponsor organisation
Direction Centrale Du Service De Sante Des Armees
Address
1 Place Alphonse Laveran
City
Paris
Postcode
75005
Country
France

Scientific contact point

Organisation
Direction Centrale Du Service De Sante Des Armees
Contact name
Chef de bureau

Public contact point

Organisation
Direction Centrale Du Service De Sante Des Armees
Contact name
Chef de bureau

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
France Ended 40 1
Rest of world 0

Investigational sites

France

1 site · Ended
Eurofins Optimed
EUROFINS OPTIMED, 1 Rue Des Essarts, 38610, Gieres

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
France 2024-01-18 2024-12-16 2024-01-18 2024-10-17

Application history

5 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-11-06 France Acceptable
2024-01-02
2024-01-02
2 SUBSTANTIAL MODIFICATION SM-1 2024-02-02 France Acceptable
2024-03-18
2024-03-18
3 NON SUBSTANTIAL MODIFICATION NSM-1 2024-05-17 France Acceptable
2024-03-18
2024-05-17
4 SUBSTANTIAL MODIFICATION SM-4 2024-05-17 France Acceptable
2024-07-05
2024-07-05
5 SUBSTANTIAL MODIFICATION SM-5 2024-07-19 France Acceptable
2024-07-30
2024-07-30