Investigating how CagriSema, semaglutide and cagrilintide regulate insulin effects in the body of people with type 2 diabetes.

2023-509483-20-00 Protocol NN9388-7782 Human pharmacology (Phase I) - Other Ended

Start 26 Apr 2024 · End 2 Feb 2026 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol NN9388-7782

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 150
Countries 1
Sites 1

Type 2 diabetes

Key facts

Sponsor
Novo Nordisk A/S
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Nutritional and Metabolic Diseases [C18]
Trial duration
26 Apr 2024 → 2 Feb 2026
Decision date (initial)
2024-04-03
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2023-509483-20-00
WHO UTN
U1111-1300-1930

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Type 2 diabetes

VersionLevelCodeTermSystem organ class
21.1 LLT 10045242 Type II diabetes mellitus 10027433

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Novo Nordisk A/S

Sponsor organisation
Novo Nordisk A/S
Address
Novo Alle 1
City
Bagsvaerd
Postcode
2880
Country
Denmark

Scientific contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission Hub

Public contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission Hub

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Ended 150 1
Rest of world 0

Investigational sites

Germany

1 site · Ended
PROFIL Institut fuer Stoffwechselforschung GmbH
N/A, Hellersbergstrasse 9, Hammfeld, Neuss

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Germany 2024-04-26 2026-02-02 2024-05-06 2025-06-27

Application history

7 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-02-08 Germany Acceptable
2024-03-27
2024-04-03
2 SUBSTANTIAL MODIFICATION SM-1 2024-05-09 Germany Acceptable 2024-05-24
3 NON SUBSTANTIAL MODIFICATION NSM-1 2024-08-06 Germany Acceptable 2024-08-06
4 SUBSTANTIAL MODIFICATION SM-2 2024-08-09 Germany Acceptable
2024-09-02
2024-09-04
5 SUBSTANTIAL MODIFICATION SM-3 2024-12-12 Germany Acceptable
2025-01-29
2025-01-31
6 SUBSTANTIAL MODIFICATION SM-4 2025-09-18 Germany Acceptable
2025-10-10
2025-10-14
7 SUBSTANTIAL MODIFICATION SM-5 2026-01-19 Germany Acceptable
2026-01-29
2026-01-30