Study on PhArmacokiNetics of first liNe Antiretrovirals in healthy Breastfeeding volunteers or women living with HIV and already on antiretrovirals

2023-510232-36-00 Protocol 114041 Human pharmacology (Phase I) - Other Ended

Start 1 Oct 2024 · End 28 Apr 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol 114041

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 20
Countries 1
Sites 1

healthy breastfeeding women

Key facts

Sponsor
Stichting Radboud University Medical Center
Participant type
Patients, Healthy volunteers
Age range
18-64 years
Gender
Female
Therapeutic area
Diseases [C] - Virus Diseases [C02]
Trial duration
1 Oct 2024 → 28 Apr 2025
Decision date (initial)
2024-09-12
Transition trial
Yes
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2023-510232-36-00
EudraCT number
2022-003715-29
ClinicalTrials.gov
NCT05648201

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

healthy breastfeeding women

VersionLevelCodeTermSystem organ class
20.1 PT 10020161 HIV infection 100000004862

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Stichting Radboud University Medical Center

Sponsor organisation
Stichting Radboud University Medical Center
Address
Geert Grooteplein Zuid 10
City
Nijmegen
Postcode
6525 GA
Country
Netherlands

Scientific contact point

Organisation
Stichting Radboud University Medical Center
Contact name
Wendy van der Wekken

Public contact point

Organisation
Stichting Radboud University Medical Center
Contact name
Wendy van der Wekken

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Netherlands Ended 20 1
Rest of world 0

Investigational sites

Netherlands

1 site · Ended
Radboud universitair medisch centrum Stichting
Pharmacy, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Netherlands 2024-10-01 2025-04-28

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-08-29 Netherlands Acceptable with conditions
2024-09-12
2024-09-12
2 SUBSTANTIAL MODIFICATION SM-4 2025-04-08 Netherlands Acceptable
2025-07-03
2025-07-03