Testing Insulin Enemas for Ulcerative Colitis: A First-Stage Clinical Trial

2023-510335-11-00 Protocol ET-RIT-02 Human pharmacology (Phase I) - Other Ended

Start 4 Feb 2025 · End 2 Sep 2025 · Status Ended · 1 EU/EEA countries · 2 sites · Protocol ET-RIT-02

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 6
Countries 1
Sites 2

Ulcerative colitis

Key facts

Sponsor
EnteroTarget ApS
Participant type
Patients
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Digestive System Diseases [C06]
Trial duration
4 Feb 2025 → 2 Sep 2025
Decision date (initial)
2024-09-06
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Ulcerative colitis

VersionLevelCodeTermSystem organ class
20.1 LLT 10024123 Left-sided ulcerative (chronic) colitis 10017947
20.0 LLT 10036789 Proctosigmoiditis 10017947
20.0 PT 10036774 Proctitis 100000004856
20.0 PT 10009900 Colitis ulcerative 100000004856

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

EnteroTarget ApS

Sponsor organisation
EnteroTarget ApS
Address
Ole Maaloees Vej 3
City
Copenhagen N
Postcode
2200
Country
Denmark

Scientific contact point

Organisation
EnteroTarget ApS
Contact name
Jørgen Olsen

Public contact point

Organisation
EnteroTarget ApS
Contact name
Jørgen Olsen

Locations

1 EU/EEA country · 2 investigational sites

By country

CountryMS statusPlanned subjectsSites
Poland Ended 6 2
Rest of world 0

Investigational sites

Poland

2 sites · Ended
Centrum Medyczne Medyk Sp. z o.o. S.K.
Gastroenterologia, Al. Tadeusza Rejtana 53, 35-326, Rzeszow
H-T.Centrum Medyczne Sp. z o.o. sp.k.
NA, Aleja Bielska 103a, 43-100, Tychy

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Poland 2025-02-04 2025-09-02 2025-04-10 2025-08-12

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-05-16 Poland Acceptable with conditions
2024-09-02
2024-09-06
2 SUBSTANTIAL MODIFICATION SM-1 2024-10-17 Poland Acceptable
2024-12-20
2024-12-23