A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3938577 in Healthy Participants and Participants with Type 1 Diabetes Mellitus.

2023-510365-10-00 Protocol J4P-MC-IYAB Human pharmacology (Phase I) - Other Ongoing, recruiting

Start 29 Apr 2024 · Status Ongoing, recruiting · 1 EU/EEA countries · 1 sites · Protocol J4P-MC-IYAB

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ongoing, recruiting
Participants planned 70
Countries 1
Sites 1

Type 1 Diabetes Mellitus

Key facts

Sponsor
Eli Lilly & Co.
Participant type
Healthy volunteers, Patients
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Nutritional and Metabolic Diseases [C18]
Trial duration
29 Apr 2024 → ongoing
Decision date (initial)
2024-04-23
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2023-510365-10-00
WHO UTN
U1111-1301-8386

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Type 1 Diabetes Mellitus

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Eli Lilly & Co.

Sponsor organisation
Eli Lilly & Co.
Address
1 Lilly Corporate Center
City
Indianapolis
Postcode
46285-0001
Country
United States

Scientific contact point

Organisation
Eli Lilly & Co.
Contact name
Lilly Clinical Trials information desk

Public contact point

Organisation
Eli Lilly & Co.
Contact name
Lilly Clinical Trials information desk

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Ongoing, recruiting 70 1
Rest of world 0

Investigational sites

Germany

1 site · Ongoing, recruiting
PROFIL Institut fuer Stoffwechselforschung GmbH
NA, Hellersbergstrasse 9, Hammfeld, Neuss

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Germany 2024-04-29 2024-05-15

Application history

5 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-02-26 Germany Acceptable
2024-04-19
2024-04-23
2 SUBSTANTIAL MODIFICATION SM-1 2024-11-21 Germany Acceptable
2025-01-15
2025-01-16
3 SUBSTANTIAL MODIFICATION SM-2 2025-03-06 Germany Acceptable
2025-03-31
2025-04-16
4 SUBSTANTIAL MODIFICATION SM-3 2025-05-21 Germany Acceptable
2025-06-12
2025-06-16
5 SUBSTANTIAL MODIFICATION SM-4 2025-10-23 Germany Acceptable
2025-11-13
2025-11-14