A Phase I Study Using Hepatic Arterial Infusion of Autologous Tumor Infiltrating Lymphocytes in Patients with Melanoma and Liver Metastases

2024-512877-28-00 Human pharmacology (Phase I) - Other Ended

Start 23 Oct 2024 · End 27 Oct 2025 · Status Ended · 1 EU/EEA countries · 1 sites

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 6
Countries 1
Sites 1

Metastases to liver

Key facts

Sponsor
Vaestra Goetalandsregionen
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Neoplasms [C04]
Trial duration
23 Oct 2024 → 27 Oct 2025
Decision date (initial)
2024-10-23
Transition trial
Yes
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2024-512877-28-00
EudraCT number
2020-006126-31
ClinicalTrials.gov
NCT04812470

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Metastases to liver

VersionLevelCodeTermSystem organ class
21.1 PT 10027457 Metastases to liver 100000004864
20.0 HLT 10027156 Skin melanomas (excl ocular) 10040785
20.0 HLT 10030052 Ocular melanomas 10029104

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Vaestra Goetalandsregionen

Sponsor organisation
Vaestra Goetalandsregionen
Address
Regionens Hus
City
Vänersborg
Postcode
462 80
Country
Sweden

Scientific contact point

Organisation
Vaestra Goetalandsregionen
Contact name
Lars Ny

Public contact point

Organisation
Vaestra Goetalandsregionen
Contact name
Lars Ny

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Sweden Ended 6 1
Rest of world 0

Investigational sites

Sweden

1 site · Ended
Sahlgrenska University Hospital-Vaestra Goetalandsregionen
Oncology, Bla Straket 5, Goteborgs Annedal, Goteborg

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Sweden 2024-10-23 2024-10-23 2024-10-23

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-10-10 Sweden Acceptable
2024-10-23
2024-10-23