A Double-Blind, Randomised, Placebo-Controlled Phase I Trial to Investigate Safety, Tolerability and Pharmacokinetics of Single Ascending Topical Doses of GZ21T in Healthy Volunteers

2024-512893-86-00 Human pharmacology (Phase I) - Other Ended

Start 6 Aug 2024 · End 31 Mar 2025 · Status Ended · 1 EU/EEA countries · 1 sites

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 41
Countries 1
Sites 1

Actinic keratosis

Key facts

Sponsor
Ankh Life Sciences Limited
Participant type
Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Skin and Connective Tissue Diseases [C17]
Trial duration
6 Aug 2024 → 31 Mar 2025
Decision date (initial)
2024-07-12
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Actinic keratosis

VersionLevelCodeTermSystem organ class
20.0 PT 10000614 Actinic keratosis 100000004858

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Ankh Life Sciences Limited

Sponsor organisation
Ankh Life Sciences Limited
Address
88 Harcourt Street
City
Dublin 2
Postcode
D02 DK18
Country
Ireland

Scientific contact point

Organisation
Ankh Life Sciences Limited
Contact name
Cameron West

Public contact point

Organisation
Ankh Life Sciences Limited
Contact name
Cameron West

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Sweden Ended 41 1
Rest of world 0

Investigational sites

Sweden

1 site · Ended
CTC Clinical Trial Consultants AB
CTC, Dag Hammarskjolds Vag 10b, Uppsala Domkyrkofors., Uppsala

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Sweden 2024-08-06 2025-03-31 2024-08-06 2025-03-13

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-04-29 Sweden Acceptable
2024-07-11
2024-07-12
2 SUBSTANTIAL MODIFICATION SM-1 2024-11-28 Sweden Acceptable
2025-01-24
2025-01-30