A study investigating the safety, absorption, and elimination of radioactively labeled RO7269162, a new compound that may potentially be used in the treatment of Alzheimer’s disease.

2024-513234-37-00 Protocol BP45325 Human pharmacology (Phase I) - Other Ended

Start 16 Oct 2024 · End 29 Jan 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol BP45325

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 10
Countries 1
Sites 1

Healthy males volunteers

Key facts

Sponsor
F. Hoffmann-La Roche AG
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male
Therapeutic area
Not possible to specify
Trial duration
16 Oct 2024 → 29 Jan 2025
Decision date (initial)
2024-10-10
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Healthy males volunteers

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

F. Hoffmann-La Roche AG

Sponsor organisation
F. Hoffmann-La Roche AG
Address
Grenzacherstrasse 124
City
Basel
Postcode
4058
Country
Switzerland

Scientific contact point

Organisation
F. Hoffmann-La Roche AG
Contact name
Trial Information System -TISL

Public contact point

Organisation
F. Hoffmann-La Roche AG
Contact name
Trial Information System -TISL

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Netherlands Ended 10 1
Rest of world 0

Investigational sites

Netherlands

1 site · Ended
Pharmaceutical Research Associates Group B.V.
Program Management, Van Swietenlaan 6, 9728 NZ, Groningen

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Netherlands 2024-10-16 2025-01-29 2024-10-16 2025-01-08

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-08-05 Netherlands Acceptable
2024-10-10
2024-10-10
2 SUBSTANTIAL MODIFICATION SM-1 2024-10-25 Netherlands Acceptable
2024-11-06
2024-11-06