A study to test how insulin NNC0471-0119 H works in the body in participants with type 1 diabetes when given by an insulin pump.

2024-513472-18-00 Protocol NN1471-7712 Human pharmacology (Phase I) - Other Ended

Start 23 Jan 2025 · End 28 Jul 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol NN1471-7712

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 43
Countries 1
Sites 1

Diabetes mellitus type 1

Key facts

Sponsor
Novo Nordisk A/S
Participant type
Patients
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Nutritional and Metabolic Diseases [C18]
Trial duration
23 Jan 2025 → 28 Jul 2025
Decision date (initial)
2024-11-27
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

External identifiers

EU CT number
2024-513472-18-00
WHO UTN
U1111-1306-8005

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Diabetes mellitus type 1

VersionLevelCodeTermSystem organ class
21.1 LLT 10045228 Type I diabetes mellitus 10027433

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Novo Nordisk A/S

Sponsor organisation
Novo Nordisk A/S
Address
Novo Alle 1
City
Bagsvaerd
Postcode
2880
Country
Denmark

Scientific contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission Hub

Public contact point

Organisation
Novo Nordisk A/S
Contact name
EU Submission Hub

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Ended 43 1
Rest of world 0

Investigational sites

Germany

1 site · Ended
PROFIL Institut fuer Stoffwechselforschung GmbH
n/a, Hellersbergstrasse 9, Hammfeld, Neuss

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Germany 2025-01-23 2025-07-28 2025-01-28 2025-07-28

Application history

4 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-10-02 Germany Acceptable
2024-11-27
2024-11-27
2 SUBSTANTIAL MODIFICATION SM-1 2024-12-13 Germany Acceptable
2025-01-03
2025-01-03
3 NON SUBSTANTIAL MODIFICATION NSM-1 2025-01-20 Germany Acceptable
2025-01-03
2025-01-20
4 SUBSTANTIAL MODIFICATION SM-2 2025-05-28 Germany Acceptable
2025-06-17
2025-06-24