A study to evaluate the safety and tolerability of JNJ-70035108 and to evaluate how long JNJ-70035108 stays in and acts on the body (pharmacokinetics) when given as single and repeated doses to healthy participants

2024-514067-25-00 Protocol 70035108EDI1001 Human pharmacology (Phase I) - First administration to humans Ended

Start 23 Sep 2024 · End 10 Mar 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol 70035108EDI1001

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - First administration to humans
Status Ended
Participants planned 99
Countries 1
Sites 1

Inflammatory Conditions

Key facts

Sponsor
Janssen Cilag International
Participant type
Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Immune System Diseases [C20]
Trial duration
23 Sep 2024 → 10 Mar 2025
Decision date (initial)
2024-09-10
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Inflammatory Conditions

VersionLevelCodeTermSystem organ class
20.0 SOC 10021428 Immune system disorders 4

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Janssen Cilag International

Sponsor organisation
Janssen Cilag International
Address
Turnhoutseweg 30
City
Beerse
Postcode
2340
Country
Belgium

Scientific contact point

Organisation
Janssen Cilag International
Contact name
CTIS Point of Contact

Public contact point

Organisation
Janssen Cilag International
Contact name
CTIS Point of Contact

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Belgium Ended 99 1
Rest of world 0

Investigational sites

Belgium

1 site · Ended
SGS Belgium
SGS Clinical Pharmacology Unit, Drie Eikenstraat 655, 2650, Edegem

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Belgium 2024-09-23 2024-09-23 2025-01-15

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-07-22 Belgium Acceptable
2024-09-06
2024-09-10
2 SUBSTANTIAL MODIFICATION SM-1 2024-09-11 Belgium Acceptable 2024-09-25