A Randomized, Double-Blind, Placebo Controlled, Multi - Center, Phase 1b Study to Evaluate the Safety and Tolerability of LIV001 in Patients with Mild-to-Moderate Active Ulcerative Colitis

2024-514520-16-00 Protocol LIV001-02 Human pharmacology (Phase I) - Other Authorised, recruitment pending

Status Authorised, recruitment pending · 1 EU/EEA countries · 3 sites · Protocol LIV001-02

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Authorised, recruitment pending
Participants planned 8
Countries 1
Sites 3

mild-to-moderate active ulcerative colitis

Key facts

Sponsor
Liveome Inc.
Participant type
Patients
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Digestive System Diseases [C06]
Decision date (initial)
2024-11-18
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

mild-to-moderate active ulcerative colitis

VersionLevelCodeTermSystem organ class
20.0 PT 10009900 Colitis ulcerative 100000004856

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Liveome Inc.

Sponsor organisation
Liveome Inc.
Address
2F 114 Central town-Ro, Yeongtong-Gu Yeongtong-Gu
City
Suwon-Si
Postcode
16506
Country
Korea, Republic of

Scientific contact point

Organisation
Liveome Inc.
Contact name
Sophie Hyun-Ja Ko

Public contact point

Organisation
Liveome Inc.
Contact name
Sophie Hyun-Ja Ko

Locations

1 EU/EEA country · 3 investigational sites

By country

CountryMS statusPlanned subjectsSites
Poland Authorised, recruitment pending 8 3
Rest of world 0

Investigational sites

Poland

3 sites · Authorised, recruitment pending
Centrum Badan Klinicznych Piotr Napora Lekarze sp.p.
Gastroenterology, Ul. Ul. Jana Dlugosza 4, 51-162, Wroclaw
Centrum Medyczne Medyk Sp. z o.o.
Gastroenterology, Al. Tadeusza Rejtana 53, 35-326, Rzeszow
Provita Poliklinika Sp. z o.o.
Gastroenterology, Baboszewska 1 Lok 2u4, 02-674, Warsaw

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-07-23 Poland Acceptable with conditions
2024-11-12
2024-11-18
2 SUBSTANTIAL MODIFICATION SM-2 2025-01-08 Poland Acceptable
2025-02-24
2025-03-02