In vivo PET of synaptic density in cognitive disorders: prospective evaluation of neuronal dysfunction and relation to symptomatology.

2024-514577-22-00 Human pharmacology (Phase I) - Other Ended

Start 12 Jul 2024 · End 8 Jul 2025 · Status Ended · 1 EU/EEA countries · 1 sites

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 150
Countries 1
Sites 1

Cognitive Disorders including Alzheimer's Disease, Frontotemporal dementia, Lewy Body Disease and psychiatric disorders.

Key facts

Sponsor
UZ Leuven
Participant type
Healthy volunteers, Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Diagnosis [E01]
Trial duration
12 Jul 2024 → 8 Jul 2025
Decision date (initial)
2024-06-19
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

External identifiers

EU CT number
2024-514577-22-00
ClinicalTrials.gov
NCT05384353

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Cognitive Disorders including Alzheimer's Disease, Frontotemporal dementia, Lewy Body Disease and psychiatric disorders.

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

UZ Leuven

Sponsor organisation
UZ Leuven
Address
Herestraat 49
City
Leuven
Postcode
3000
Country
Belgium

Scientific contact point

Organisation
UZ Leuven
Contact name
Koen Van Laere

Public contact point

Organisation
UZ Leuven
Contact name
Koen Van Laere

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Belgium Ended 150 1
Rest of world 0

Investigational sites

Belgium

1 site · Ended
UZ Leuven
Nuclear Medicine, Herestraat 49, 3000, Leuven

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Belgium 2024-07-12 2024-07-12 2025-05-28

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-06-12 Belgium Acceptable
2024-06-19
2024-06-19