Clinical study to compare the therapeutic effects of two ointments with active substances betamethasone dipropionate and salicylic acid and of one ointment without active substances for patients with chronic stable plaque poriasis

2024-514788-24-00 Protocol 20-01/BetaSal-S Therapeutic confirmatory (Phase III) Ended

Start 20 Sep 2022 · End 25 Aug 2025 · Status Ended · 1 EU/EEA countries · 13 sites · Protocol 20-01/BetaSal-S

Overview

Sponsor-declared trial summary

Phase Therapeutic confirmatory (Phase III)
Status Ended
Participants planned 306
Countries 1
Sites 13

Chronic stable plaque psoriasis

Key facts

Sponsor
Dermapharm AG
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Skin and Connective Tissue Diseases [C17]
Trial duration
20 Sep 2022 → 25 Aug 2025
Decision date (initial)
2024-08-12
Transition trial
Yes
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

External identifiers

EU CT number
2024-514788-24-00
EudraCT number
2020-004081-19

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Chronic stable plaque psoriasis

VersionLevelCodeTermSystem organ class
20.0 LLT 10050576 Psoriasis vulgaris 10040785

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Dermapharm AG

Sponsor organisation
Dermapharm AG
Address
Lil-Dagover-Ring 7, Geiselgasteig Geiselgasteig
City
Gruenwald
Postcode
82031
Country
Germany

Scientific contact point

Organisation
Dermapharm AG
Contact name
Department of Clinical Research

Public contact point

Organisation
Dermapharm AG
Contact name
Department of Clinical Research

Locations

1 EU/EEA country · 13 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Ended 306 13
Rest of world 0

Investigational sites

Germany

13 sites · Ended
Hautarztzentrum Hamm
Hautarztzentrum Hamm, Friedrichstraße 20, 59065, Hamm
Praxis Dr. med. Abdou Zarzour
Praxis Dr. med. Abdou Zarzour, Große Steinstr. 12, 06108, Halle
Haut-und Lasercentrum Potsdam - Dr. med. Tanja Fischer
Haut-und Lasercentrum Potsdam, Kurfürstenstr. 40, 14467, Potsdam
Gemeinschaftspraxis Weber & Crainic
Gemeinschaftspraxis R. Weber & A. Crainic, Böheimstrasse 8, 86153, Augsburg
Praxis Fuer Dermatologie Und Venerologie
Praxis für Dermatologie und Venerologie, Hauptstrasse 36a, Innere Neustadt, Dresden
Hautzentrum Dülmen
Pro Derma Hautzentrum Dülmen, Vollenstr. 8, 48249, Dülmen
Durani Cosmetics GmbH
Durani Cosmetics GmbH, Grüne Meile 56, 69115, Heidelberg
Fachaerztliche Gemeinschaftspraxis fuer Dermatologie Und Venerologie Allergologie Umweltmedizin Lasermedizin GbR
Dermatologische Gemeinschaftspraxis Mahlow, Am Bahnhof 1, Mahlow, Blankenfelde-Mahlow
Hautarztpraxis Dr. Offers und Dr. Adamini
Hautarztpraxis Dr. Offers und Dr. Adamini, Gravenhorster Str. 5, 49477, Ibbenbüren
Hautarztpraxis Dr. Wilfried Steinborn
Hautarztpraxis Dr. Wilfried Steinborn, Theresienplatz 8, 94315, Straubing
Praxis Dr. Julia Reichle
Praxis Dr. Julia Reichle, Berliner Allee 96, 13088, Berlin
Studienzentrum Dr. med. Beate Schwarz Dermatologie und Allergologie
NA, Bismarckstrasse 49, 89129, Langenau
Derma Science GmbH
NA, Hohe Bleichen 10, 20354, Hamburg

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Germany 2022-09-20 2025-08-25 2022-10-04 2025-08-04

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-07-30 Germany Acceptable
2024-08-08
2024-08-12
2 SUBSTANTIAL MODIFICATION SM-1 2025-01-31 Germany Acceptable 2025-02-06